Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.71 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31685892 | 1.00 | TRPM8 (0.71) | TRPM8EPHX1MAPTTRPA1METAP2 | |
| SCHEMBL18541154 | 1.00 | TRPM8 (0.71) | TRPM8EPHX1MAPTTRPA1METAP2 | |
| SCHEMBL358359 | 1.00 | TRPM8 (0.71) | TRPM8EPHX1MAPTTRPA1METAP2 | |
| SCHEMBL722923 | 1.00 | TRPM8 (0.71) | TRPM8EPHX1MAPTTRPA1METAP2 | |
| SCHEMBL1115691 | 1.00 | TRPM8 (0.71) | TRPM8EPHX1MAPTTRPA1METAP2 | |
| SCHEMBL722922 | 1.00 | TRPM8 (0.71) | TRPM8EPHX1MAPTTRPA1METAP2 | |
| SCHEMBL724576 | 0.91 | TRPM8 (0.60) | TRPM8EPHX1MAPTTRPA1TRPV1 | |
| SCHEMBL724575 | 0.91 | TRPM8 (0.60) | TRPM8EPHX1MAPTTRPA1TRPV1 | |
| SCHEMBL3956252 | 0.91 | TRPM8 (0.60) | TRPM8EPHX1MAPTTRPA1TRPV1 | |
| SCHEMBL2855494 | 0.89 | TRPM8 (0.57) | TRPM8EPHX1MAPTTRPA1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103006509-B | Emulsion compositions and apply its wet tissue | GOLD HONG YE PAPER Co.,Ltd. (CN) | 2016-03-02 | — | — | CN | claimed |
| CN-102716043-B | Cool and refreshing emulsion and moist towelette | GOLD HONG YE PAPER CO LTD | 2014-06-18 | — | — | CN | claimed |
| CN-103006509-A | Emulsion composition and wet tissue applying emulsion composition | GOLD HONG YE PAPER CO LTD | 2013-04-03 | — | — | CN | claimed |
| CN-102716043-A | Cool and refreshing emulsion and moist towelette | GOLD HONG YE PAPER CO LTD | 2012-10-10 | — | — | CN | claimed |
| US-12233139-B2 | Oral care compositions containing a gel network phase | THE PROCTER & GAMBLE COMPANY (US) | 2025-02-25 | — | — | US | disclosed |
| EP-4337157-A1 | ORAL CARE COMPOSITIONS COMPRISING BLOCK COPOLYMER | The Procter & Gamble Company (US) | 2024-03-20 | — | — | EP | disclosed |
| EP-4216915-A1 | ORAL CARE COMPOSITION COMPRISING HOPS AND FLAVOR | The Procter & Gamble Company (US) | 2023-08-02 | — | — | EP | disclosed |
| EP-2346475-B2 | PERSONAL CARE COMPOSITIONS PROVIDING ENHANCED COOLING SENSATION | PROCTER & GAMBLE (US) | 2023-04-19 | — | — | EP | disclosed |
| US-20230104890-A1 | Oral Care Compositions Containing A Gel Network Phase | PROCTER & GAMBLE (US) | 2023-04-06 | — | — | US | disclosed |
| US-11517509-B2 | Oral care compositions containing a gel network phase | THE PROCTER & GAMBLE COMPANY (US) | 2022-12-06 | — | — | US | disclosed |
| US-20220370334-A1 | Oral Care Compositions Comprising Block Copolymer | THE PROCTER & GAMBLE COMPANY | 2022-11-24 | — | — | US | disclosed |
| CN-109843385-B | Skin engaging member comprising ethylene vinyl acetate and fragrance | 吉列有限责任公司 | 2022-06-03 | — | — | CN | disclosed |
| EP-2313070-A1 | SOLUTION OF MENTHANE CARBOXAMIDES FOR USE IN CONSUMER PRODUCTS | The Procter & Gamble Company (US) | 2011-04-27 | — | — | EP | disclosed |
| WO-2010059289-A1 | PERSONAL CARE COMPOSITIONS PROVIDING ENHANCED COOLING SENSATION | THE PROCTER & GAMBLE COMPANY (US) | 2010-05-27 | — | — | WO | disclosed |
| US-20100086498-A1 | Personal Care Compositions Providing Enhanced Cooling Sensation | THE PROCTER & GAMBLE COMPANY | 2010-04-08 | — | — | US | disclosed |
| US-20100076080-A1 | Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products | THE PROCTER & GAMBLE COMPANY | 2010-03-25 | — | — | US | disclosed |
| WO-2010019729-A1 | SOLUTION OF MENTHANE CARBOXAMIDES FOR USE IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2010-02-18 | — | — | WO | disclosed |
| US-20100040563-A1 | Solubilization of Cyclohexane-Based Carboxamide Derivatives for Use as Sensates in Consumer Products | THE PROCTER & GAMBLE COMPANY | 2010-02-18 | — | — | US | disclosed |
| WO-2010019730-A1 | SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2010-02-18 | — | — | WO | disclosed |
| US-20080227857-A1 | N-Alkylcarbonyl-Amino Acid Ester and N-Alkylcarbonyl-Amino Lactone Compounds and Their Use | WEI EDWARD TAK | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12233139-B2 | Oral care compositions containing a gel network phase | FLNA, FLNB, FRG1 | TRPM8 4193/4885EPHX1 2162/4885MAPT 895/4885 |
| US-20230104890-A1 | Oral Care Compositions Containing A Gel Network Phase | FLNA, FLNB, FRG1 | TRPM8 4193/4885EPHX1 2162/4885MAPT 895/4885 |
| US-11517509-B2 | Oral care compositions containing a gel network phase | FLNA, FLNB, AP1G1 | TRPM8 3630/4885EPHX1 2523/4885MAPT 330/4885 |
| US-20100040563-A1 | Solubilization of Cyclohexane-Based Carboxamide Derivatives for Use as Sensates in Consumer Products | CUTA, TAS2R8, TAS2R38 | TRPM8 76/4885EPHX1 3890/4885MAPT 3219/4885 |
| US-20080227857-A1 | N-Alkylcarbonyl-Amino Acid Ester and N-Alkylcarbonyl-Amino Lactone Compounds and Their Use | TRPA1, TRPV1, CYSLTR1 | TRPM8 22/4885EPHX1 1517/4885MAPT 4137/4885 |
| US-20100086498-A1 | Personal Care Compositions Providing Enhanced Cooling Sensation | TRPA1, TRPV1, TRPM2 | TRPM8 7/4885EPHX1 4795/4885MAPT 1314/4885 |
| US-20220370334-A1 | Oral Care Compositions Comprising Block Copolymer | POLQ, POLB, TAS2R40 | TRPM8 3531/4885EPHX1 1522/4885MAPT 1262/4885 |
| US-20100076080-A1 | Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products | NISCH, TRPM4, TRPM8 | TRPM8 3/4885EPHX1 528/4885MAPT 1429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.