SCHEMBL395683

SCHEMBL395683

Cl[Ti](Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.38
HTR6 P50406 1/20 0.37
SIGMAR1 Q99720 2/20 0.31
KDM4E B2RXH2 2/20 0.31
BRD4 O60885 1/20 0.31
CCL2 P13500 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CHRM2 P08172 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene SCHEMBL9409610 0.96 HTR2A (0.35) HTR2AHTR6
SCHEMBL1929586 0.87 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL6906407 0.85 HTR6 (0.32) HTR2AHTR6CYP2D6
SCHEMBL4373641 0.79 RET (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL8656018 0.79 SIGMAR1 (0.34) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL3699818 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL7637233 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL31427622 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL5368513 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL7196286 0.78 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3162816-B1 METHOD FOR MANUFACTURING HYDROGENATED POLYMER KURARAY CO (JP) 2019-01-02 EP claimed
US-20170204214-A1 METHOD FOR MANUFACTURING HYDROGENATED POLYMER KURARAY CO., LTD. (JP) 2017-07-20 US claimed
EP-3162816-A1 METHOD FOR MANUFACTURING HYDROGENATED POLYMER Kuraray Co., Ltd. (JP) 2017-05-03 EP claimed
US-7186782-B2 Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2007-03-06 US claimed
US-20060041079-A1 Hydrogenation catalyst composition and process for hydrogenation of conjugated diene polymer TSRC CORPORATION 2006-02-23 US claimed
US-6881797-B2 Process for hydrogenation of conjugated diene polymer TSRC CORPORATION (TW) 2005-04-19 US claimed
US-20040082727-A1 Process for hydrogenation of conjugated diene polymer TSRC CORPORATION (CN) 2004-04-29 US claimed
US-6143844-A POLYMERIZING 1-OLEFINS BY CONTACING SLURRY OR GAS PHASE IN REACTORS WITH HETEROGENOUS CATALYST MADE BY CHEMISORBING IN A REACTION CHAMBER VAPORIZED METALLOCENE ONTO AN INORGANIC SUPPORT AND REMOVING UNREACTED METALLOCENE BOREALIS A/S (DK) 2000-11-07 US claimed
EP-0731729-B1 METHOD FOR PREPARING A CATALYST FOR OLEFIN POLYMERIZATION BOREALIS AS (DK) 2000-03-01 EP claimed
US-5767032-A TREATING A SOLID INORGANIC SUPPORT WITH A VAPORIZED METALLOCENE; COORDINATION CATALYSTS; REGULATION OF CATALYST ACTIVITY TO REGULATE POLYMER MOLECULAR WEIGHT AND MOLECULAR WEIGHT DISTRIBUTION BOREALIS A/S (DK) 1998-06-16 US claimed
EP-0731729-A1 CATALYST FOR OLEFIN POLYMERIZATION AND A METHOD FOR THE MANUFACTURE THEREOF BOREALIS A/S (DK) 1996-09-18 EP claimed
EP-0474391-B1 Polyolefins NIPPON OIL CO LTD (JP) 1995-10-25 EP claimed
WO-1995015216-A1 CATALYST FOR OLEFIN POLYMERIZATION AND A METHOD FOR THE MANUFACTURE THEREOF BOREALIS A/S (DK) 1995-06-08 WO claimed
EP-0412750-B1 Production of alpha-olefin polymers MITSUBISHI PETROCHEMICAL CO (JP) 1995-02-15 EP claimed
US-5104838-A Titanium-containing solid catalyst component MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1992-04-14 US claimed
EP-0474391-A2 Polyolefins NIPPON OIL CO. LTD. (JP) 1992-03-11 EP claimed
EP-0412750-A2 Production of alpha-olefin polymers MITSUBISHI CHEMICAL CORPORATION (JP) 1991-02-13 EP claimed
US-20220324895-A1 DEPOLYMERIZATION AND VALORIZATION OF A BIOPOLYMER UNIV NEW YORK (US) 2022-10-13 US disclosed
EP-0108847-A1 Production of acetic acid, propionic acid and their esters TEXACO DEVELOPMENT CORPORATION (US) 1984-05-23 EP disclosed
US-4362822-A FROM HYDROGEN AND CARBON MONOXIDE USING CATALYST CONTAINING A RUTHENIUM COMPOUND, HALOGEN CONTAINING TITANIUM OR ZIRCONIUM SALT DISPERSED IN QUATENARY PHOSPHONIUM OR AMMONIUM SALT TEXACO INC. (US) 1982-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220324895-A1 DEPOLYMERIZATION AND VALORIZATION OF A BIOPOLYMER ALG1, PPOX, MANBA HTR2A 4669/4885HTR6 4781/4885SIGMAR1 4213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.