Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 6/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 8/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2175477 | 0.77 | MTNR1A (0.41) | NR4A2MTNR1AMTNR1BNQO2 | |
| SCHEMBL6496739 | 0.74 | CYP2A6 (0.50) | NR4A2CREBBPALDH1A1 | |
| SCHEMBL4599128 | 0.73 | MEN1 (0.47) | ALDH1A1 | |
| SCHEMBL3973107 | 0.71 | ERN1 (0.45) | ALDH1A1 | |
| SCHEMBL3953673 | 0.71 | MTNR1A (0.53) | NR4A2MTNR1AMTNR1BCREBBP | |
| SCHEMBL25232528 | 0.70 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL21416073 | 0.70 | ALDH1A1 (0.42) | NR4A2ALDH1A1 | |
| SCHEMBL20943928 | 0.70 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL29570755 | 0.70 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL24723620 | 0.69 | HTR2A (0.55) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009030270-A1 | DIHYDROINDOLE DERIVATIVES USEFUL IN PARKINSON'S DISEASE | NOVARTIS AG (CH) | 2009-03-12 | — | — | WO | disclosed |