Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.44 |
| ▸ | TUBB | P07437 | 3/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6421659 | 0.82 | NR4A2 (0.49) | MTNR1AMTNR1BHTR3EHTR3BHTR3A | |
| SCHEMBL31065131 | 0.81 | NR4A2 (0.49) | MTNR1AMTNR1BNR4A2CREBBPP2RX7 | |
| SCHEMBL21643735 | 0.81 | NR4A2 (0.49) | MTNR1AMTNR1BNR4A2CREBBPP2RX7 | |
| SCHEMBL13987128 | 0.81 | NR4A2 (0.47) | MTNR1AMTNR1BHTR3EHTR3BHTR3A | |
| SCHEMBL2175477 | 0.80 | MTNR1A (0.41) | MTNR1AMTNR1BHTR3EHTR3BHTR3A | |
| SCHEMBL6421662 | 0.79 | NR4A2 (0.43) | MTNR1AMTNR1BHTR3EHTR3BHTR3A | |
| SCHEMBL29337712 | 0.78 | L3MBTL1 (0.44) | MTNR1AMTNR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL30285551 | 0.78 | L3MBTL1 (0.44) | MTNR1AMTNR1BTUBB4ATUBBTUBA3C | |
| SCHEMBL31108646 | 0.77 | ALOX5 (0.45) | MTNR1AMTNR1BHTR3EHTR3BHTR3A | |
| SCHEMBL7655120 | 0.75 | MTNR1A (0.38) | MTNR1AMTNR1BHTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009030270-A1 | DIHYDROINDOLE DERIVATIVES USEFUL IN PARKINSON'S DISEASE | NOVARTIS AG (CH) | 2009-03-12 | — | — | WO | disclosed |