Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3313039 | 0.78 | L3MBTL1 (0.45) | L3MBTL1MAPTMAPK1NPSR1DNM1 | |
| SCHEMBL9543322 | 0.77 | MAPT (0.34) | L3MBTL1MAPTMAPK1NPSR1SLC6A2 | |
| SCHEMBL3307512 | 0.76 | HRH3 (0.41) | L3MBTL1MAPTMAPK1NPSR1HRH3 | |
| SCHEMBL3312346 | 0.76 | L3MBTL1 (0.43) | L3MBTL1MAPTMAPK1NPSR1DNM1 | |
| SCHEMBL5839699 | 0.73 | OPRM1 (0.43) | L3MBTL1MAPTMAPK1NPSR1HRH3 | |
| SCHEMBL8390873 | 0.73 | OPRM1 (0.43) | L3MBTL1MAPTMAPK1NPSR1HRH3 | |
| SCHEMBL3308643 | 0.73 | HRH3 (0.38) | L3MBTL1MAPTMAPK1NPSR1DNM1 | |
| SCHEMBL24688643 | 0.72 | HRH3 (0.40) | L3MBTL1MAPTMAPK1NPSR1HRH3 | |
| SCHEMBL3160023 | 0.72 | HRH3 (0.40) | L3MBTL1MAPTMAPK1NPSR1HRH3 | |
| SCHEMBL9370536 | 0.72 | HRH3 (0.40) | L3MBTL1MAPTMAPK1NPSR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1002794-B1 | 4-¬(Aryl)(aryloxy)methyl piperidine derivatives and their use as serotonin and/or noradrenaline reuptake inhibitors | FAES FABRICA ESPANOLA DE PRODU (ES) | 2009-02-04 | — | — | EP | disclosed |