Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | LAP3 | P28838 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8390873 | 1.00 | OPRM1 (0.43) | OPRM1L3MBTL1MAPTMAPK1NPSR1 | |
| SCHEMBL7771636 | 0.94 | HRH3 (0.42) | OPRM1L3MBTL1MAPTMAPK1NPSR1 | |
| SCHEMBL9417420 | 0.94 | OPRM1 (0.44) | OPRM1L3MBTL1MAPTMAPK1NPSR1 | |
| SCHEMBL2914564 | 0.91 | HRH3 (0.40) | OPRM1L3MBTL1MAPTMAPK1NPSR1 | |
| SCHEMBL1615233 | 0.89 | OPRM1 (0.48) | OPRM1MAPTSPHK1TP53LAP3 | |
| SCHEMBL28298745 | 0.87 | OPRM1 (0.46) | OPRM1MAPTSPHK1TP53LAP3 | |
| SCHEMBL1614413 | 0.87 | OPRM1 (0.46) | OPRM1MAPTSPHK1TP53LAP3 | |
| SCHEMBL28298671 | 0.87 | OPRM1 (0.46) | OPRM1MAPTSPHK1TP53LAP3 | |
| SCHEMBL1615271 | 0.87 | OPRM1 (0.46) | OPRM1MAPTSPHK1TP53LAP3 | |
| SCHEMBL1614359 | 0.87 | OPRM1 (0.46) | OPRM1MAPTSPHK1TP53LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6252115-B1 | ADDING TO THE DISTILLATION MIXTURE AN INERT COMPOUND HAVING A BOILING POINT HIGHER THAN THE AMINE | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | claimed |
| EP-0964847-A1 | METHOD FOR SEPARATING AN IMINE FROM A MIXTURE CONTAINING AN AMINE AND AN IMINE | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-22 | — | — | EP | claimed |
| WO-1998034900-A1 | METHOD FOR SEPARATING AN IMINE FROM A MIXTURE CONTAINING AN AMINE AND AN IMINE | BASF AKTIENGESELLSCHAFT (DE) | 1998-08-13 | — | — | WO | claimed |
| US-7147757-B2 | Method for separating an azepine derivative out of a mixture containing an amine an azepine derivative | BASF AKTIENGESELLSCHAFT (DE) | 2006-12-12 | — | — | US | disclosed |
| CN-1234685-C | Method for separation azepine derivative out of mixture contg. amine and azepine derivative | BASF AG (DE) | 2006-01-04 | — | — | CN | disclosed |
| CN-1416418-A | Method for separation azepine derivative out of mixture contg. amine and azepine derivative | BASF AG (DE) | 2003-05-07 | — | — | CN | disclosed |
| US-20030023083-A1 | Method for separating an azepine derivative out of a mixture containing an amine an azepine derivative | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-30 | — | — | US | disclosed |
| EP-1261580-A1 | METHOD FOR SEPARATING AN AZEPINE DERIVATIVE OUT OF A MIXTURE CONTAINING AN AMINE AND AN AZEPINE DERIVATIVE | BASF AKTIENGESELLSCHAFT (DE) | 2002-12-04 | — | — | EP | disclosed |
| US-6300497-B1 | DISTILLATION | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-09 | — | — | US | disclosed |
| WO-2001066514-A1 | METHOD FOR SEPARATING AN AZEPINE DERIVATIVE OUT OF A MIXTURE CONTAINING AN AMINE AND AN AZEPINE DERIVATIVE | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-13 | — | — | WO | disclosed |
| EP-1064266-A2 | METHOD FOR SEPARATING AN AZEPINE DERIVATIVE FROM A MIXTURE CONTAINING AN AMINE AND AN AZEPINE DERIVATIVE | BASF AKTIENGESELLSCHAFT (DE) | 2001-01-03 | — | — | EP | disclosed |
| WO-1999048872-A3 | METHOD FOR SEPARATING AN AZEPINE DERIVATIVE FROM A MIXTURE CONTAINING AN AMINE AND AN AZEPINE DERIVATIVE | BASF AG (DE) | 1999-12-02 | — | — | WO | disclosed |
| WO-1999048872-A2 | METHOD FOR SEPARATING AN AZEPINE DERIVATIVE FROM A MIXTURE CONTAINING AN AMINE AND AN AZEPINE DERIVATIVE | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030023083-A1 | Method for separating an azepine derivative out of a mixture containing an amine an azepine derivative | HTR5A, HTR3B, HTR3E | OPRM1 322/4885L3MBTL1 4844/4885MAPT 2591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.