Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL137155 | 0.97 | ALDH1A1 (0.67) | ALDH1A1ATMTSHRHPGDNAAA | |
| SCHEMBL5501929 | 0.97 | ALDH1A1 (0.67) | ALDH1A1ATMTSHRHPGDNAAA | |
| SCHEMBL28787473 | 0.97 | ALDH1A1 (0.67) | ALDH1A1ATMTSHRHPGDNAAA | |
| SCHEMBL5501926 | 0.94 | ALDH1A1 (0.64) | ALDH1A1ATMTSHRHPGDNAAA | |
| SCHEMBL28131973 | 0.94 | ALDH1A1 (0.64) | ALDH1A1ATMTSHRHPGDNAAA | |
| SCHEMBL1979194 | 0.92 | TSHR (0.65) | ALDH1A1ATMTSHRHPGDNAAA | |
| SCHEMBL1070844 | 0.92 | ALDH1A1 (0.61) | ALDH1A1ATMTSHRHPGDNAAA | |
| SCHEMBL7622799 | 0.90 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDNAAA | |
| SCHEMBL1981094 | 0.90 | TSHR (0.69) | ALDH1A1ATMTSHRNAAAHCAR2 | |
| Acetic Acid SCHEMBL28461572 | 0.90 | ALDH1A1 (0.65) | ALDH1A1ATMTSHRHPGDNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261398-B2 | USE OF FLUORINATED KETONES IN FIRE EXTINGUISHING COMPOSITIONS | 3M INNOVATIVE PROPERTIES CO (US) | 2016-04-13 | — | — | EP | disclosed |
| EP-1362619-B1 | Fire extinguishing composition | 3M INNOVATIVE PROPERTIES CO (US) | 2009-07-15 | — | — | EP | disclosed |
| EP-1261398-B1 | USE OF FLUORINATED KETONES IN FIRE EXTINGUISHING COMPOSITIONS | 3M INNOVATIVE PROPERTIES CO (US) | 2004-09-29 | — | — | EP | disclosed |
| EP-1362619-A2 | Fire extinguishing composition | 3M Innovative Properties Company (US) | 2003-11-19 | — | — | EP | disclosed |
| US-6630075-B2 | Applying fluorinated ketone containing </= 2 hydrogen atoms and having a boiling point 0-150 degrees c | 3M INNOVATIVE PROPERTIES COMPANY | 2003-10-07 | — | — | US | disclosed |
| US-20030089877-A1 | Use of fluorinated ketones in fire extinguishing compositions | 3M INNOVATIVE PROPERTIES COMPANY | 2003-05-15 | — | — | US | disclosed |
| EP-1261398-A2 | USE OF FLUORINATED KETONES IN FIRE EXTINGUISHING COMPOSITIONS | 3M Innovative Properties Company (US) | 2002-12-04 | — | — | EP | disclosed |
| US-6478979-B1 | Use of fluorinated ketones in fire extinguishing compositions | 3M INNOVATIVE PROPERTIES COMPANY | 2002-11-12 | — | — | US | disclosed |
| WO-2001005468-A2 | USE OF FLUORINATED KETONES IN FIRE EXTINGUISHING COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030089877-A1 | Use of fluorinated ketones in fire extinguishing compositions | PFAS, FLNA, PFKFB2 | ALDH1A1 1599/4885ATM 2959/4885TSHR 2164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.