Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA4 | P22748 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 5/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6744243 | 0.89 | CA1 (0.44) | CA1CA2CA4CA9SIGMAR1 | |
| SCHEMBL8678902 | 0.80 | CA1 (0.50) | CA1CA2CA4CA9KMT2A | |
| SCHEMBL2253695 | 0.80 | NR1H2 (0.44) | CA1CA2CA4CA9 | |
| SCHEMBL28061774 | 0.80 | HTR6 (0.42) | CA1CA2CA4CA9SIGMAR1 | |
| Fluoride SCHEMBL28061775 | 0.78 | HTR6 (0.41) | CA1CA2CA4CA9SIGMAR1 | |
| SCHEMBL30597535 | 0.77 | ALDH1A1 (0.48) | CA1CA2CA9SIGMAR1ALDH1A1 | |
| SCHEMBL3902529 | 0.77 | CA1 (0.44) | CA1CA2CA4CA9SIGMAR1 | |
| SCHEMBL30407459 | 0.77 | CHRM2 (0.43) | HTR6CHRM2CHRM1KAT6AALDH1A1 | |
| SCHEMBL29060773 | 0.76 | CA1 (0.38) | CA1CA2CA4CA9CHRM2 | |
| SCHEMBL5636647 | 0.76 | MEN1 (0.34) | KMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079756-A2 | SYNTHETIC PEPTIDE AMIDES AND DIMERS THEREOF | Cara Therapeutics, Inc. (US) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008060552-A2 | SYNTHETIC PEPTIDE AMIDES AND DIMERS THEREOF | CARA THERAPEUTICS, INC. (US) | 2008-05-22 | — | — | WO | disclosed |