Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2827168 | 0.90 | TYR (0.43) | TYRESR1ESR2KDM4EMAPT | |
| SCHEMBL16322178 | 0.87 | ESR1 (0.36) | HTTSMN1; SMN2LMNASLC5A1SLC5A2 | |
| SCHEMBL5204089 | 0.84 | TYR (0.42) | TYRLMNASLC5A1SLC5A2 | |
| SCHEMBL2331746 | 0.84 | TYR (0.39) | TYRLMNASLC5A1SLC5A2MAPT | |
| SCHEMBL4686426 | 0.83 | TYR (0.57) | TYRSMN1; SMN2KDM4EMAPT | |
| SCHEMBL7723547 | 0.82 | TYR (0.40) | TYRLMNAPOLBKDM4EMAPT | |
| SCHEMBL26999419 | 0.81 | ESR1 (0.40) | LMNAESR1ESR2KDM4EMAPT | |
| SCHEMBL3955351 | 0.80 | MEN1 (0.51) | TYRSMN1; SMN2LMNASLC5A1SLC5A2 | |
| SCHEMBL8549265 | 0.80 | GABRA1 (0.38) | HTTSMN1; SMN2LMNAPOLBKDM4E | |
| SCHEMBL14855983 | 0.79 | TYR (0.47) | TYRLMNAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3010502-A1 | AZETIDINE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | Seragon Pharmaceuticals, Inc. (US) | 2016-04-27 | — | — | EP | disclosed |
| WO-2014205136-A1 | AZETIDINE ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | SERAGON PHARMACEUTICALS, INC. (US) | 2014-12-24 | — | — | WO | disclosed |
| WO-2009026658-A1 | PPAR AGONISTS | THE UNIVERSITY OF SYDNEY (AU) | 2009-03-05 | — | — | WO | disclosed |
| WO-2009026657-A1 | FLAVONOID PPAR AGONISTS | THE UNIVERSITY OF SYDNEY (AU) | 2009-03-05 | — | — | WO | disclosed |
| CN-1671373-A | Compounds for inhibiting ALDH | ENDOWMENT FOR RES IN HUMAN BIO (US) | 2005-09-21 | — | — | CN | disclosed |