Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2827168 | 0.90 | TYR (0.43) | TYRMAPTALDH1A1 | |
| SCHEMBL5204089 | 0.84 | TYR (0.42) | TYRLMNASLC5A1SLC5A2 | |
| SCHEMBL3958574 | 0.84 | TYR (0.39) | TYRMAPTLMNASLC5A1SLC5A2 | |
| SCHEMBL4686426 | 0.83 | TYR (0.57) | TYRMAPTGAAMEN1ALDH1A1 | |
| SCHEMBL7723547 | 0.82 | TYR (0.40) | TYRMAPTRAB9ALMNAMEN1 | |
| SCHEMBL26999421 | 0.81 | ALOX15 (0.54) | MAPTLMNAGAAMEN1ALDH1A1 | |
| SCHEMBL3955351 | 0.80 | MEN1 (0.51) | TYRNPC1MAPTRAB9ALMNA | |
| SCHEMBL6631529 | 0.80 | GABRA1 (0.38) | NPC1MAPTRAB9ALMNAMEN1 | |
| SCHEMBL14855983 | 0.79 | TYR (0.47) | TYRRAB9ALMNA | |
| SCHEMBL19806929 | 0.78 | ALOX15 (0.44) | TYRNPC1MAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2533638-A1 | NOVEL S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS | N30 Pharmaceuticals, Inc. (US) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011100433-A1 | NOVEL S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS | N30 PHARMACEUTICALS, LLC (US) | 2011-08-18 | — | — | WO | disclosed |