SCHEMBL395859

SCHEMBL395859

C=C(c1ccccc1OCc1ccc(Cl)cc1Cl)n1ccnc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 2/20 0.72
ADORA3 P0DMS8 2/20 0.72
TBXA2R P21731 2/20 0.72
SLC6A2 P23975 2/20 0.72
HTR2A P28223 2/20 0.72
SLC6A4 P31645 2/20 0.72
ADRA1A P35348 2/20 0.72
HTR2B P41595 2/20 0.72
KCNH2 Q12809 2/20 0.72
NR1I2 O75469 1/20 0.72
NR3C1 P04150 1/20 0.72
CNR1 P21554 1/20 0.72
HTR2C P28335 1/20 0.72
OPRK1 P41145 1/20 0.72
PDE4D Q08499 1/20 0.72
ADRB3 P13945 12/20 0.52
ADRB2 P07550 11/20 0.52
ADRB1 P08588 11/20 0.52
FABP3 P05413 1/20 0.47
FABP4 P15090 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30680200 1.00 HTR1A (0.72) HTR1AADORA3TBXA2RSLC6A2HTR2A
SCHEMBL11090316 0.89 NR1I2 (0.67) HTR1AADORA3TBXA2RSLC6A2HTR2A
SCHEMBL9825342 0.89 ADORA3 (0.57) HTR1AADORA3TBXA2RSLC6A2HTR2A
SCHEMBL8882786 0.85 ADORA3 (0.55) HTR1AADORA3TBXA2RSLC6A2HTR2A
SCHEMBL8882790 0.85 ADORA3 (0.55) HTR1AADORA3TBXA2RSLC6A2HTR2A
SCHEMBL9798370 0.84 NR1I2 (0.57) HTR1AADORA3TBXA2RSLC6A2HTR2A
SCHEMBL11090539 0.84 NR1I2 (0.78) HTR1AADORA3TBXA2RSLC6A2HTR2A
SCHEMBL2454428 0.84 ADORA3 (0.54) HTR1AADORA3TBXA2RSLC6A2HTR2A
SCHEMBL2454425 0.84 ADORA3 (0.54) HTR1AADORA3TBXA2RSLC6A2HTR2A
Croconazole SCHEMBL34369 0.83 NR1I2 (1.00) HTR1AADORA3TBXA2RSLC6A2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 698 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12391729-B2 Fusion proteins, recombinant bacteria, and methods for using recombinant bacteria SPOGEN BIOTECH INC. (US) 2025-08-19 US claimed
US-20240199709-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA SPOGEN BIOTECH INC (US) 2024-06-20 US claimed
US-11905315-B2 Fusion proteins, recombinant bacteria, and methods for using recombinant bacteria SPOGEN BIOTECH INC. (US) 2024-02-20 US claimed
US-20210179672-A1 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA GENISYS CREDIT UNION 2021-06-17 US claimed
EP-2533633-B1 FUNGICIDAL MIXTURES LANXESS DISTRIB GMBH (DE) 2017-02-01 EP claimed
WO-2016044655-A2 FUSION PROTEINS, RECOMBINANT BACTERIA, AND METHODS FOR USING RECOMBINANT BACTERIA SPOGEN BIOTECH INC. (US) 2016-03-24 WO claimed
US-20130195997-A1 FUNGICIDAL MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2013-08-01 US claimed
EP-2533633-A2 FUNGICIDAL MIXTURES LANXESS Distribution GmbH (DE) 2012-12-19 EP claimed
EP-2460408-A1 Nematicidal compositions deVGen N.V. (BE) 2012-06-06 EP claimed
US-20110319435-A1 FUNGICIDE MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2011-12-29 US claimed
WO-2011095492-A2 FUNGICIDAL MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2011-08-11 WO claimed
EP-2315522-A2 FORMATE-CONTAINING FUNGICIDE MIXTURES LANXESS Distribution GmbH (DE) 2011-05-04 EP claimed
EP-2153720-A1 Fungicide mixtures comprising formate LANXESS Distribution GmbH (DE) 2010-02-17 EP claimed
WO-2010015635-A2 FUNGICIDE MIXTURES LANXESS DISTRIBUTION GMBH (DE) 2010-02-11 WO claimed
US-4483866-A FUNGICIDE SHIONOGI & CO., LTD. (JP) 1984-11-20 US claimed
US-12630484-B2 Methods for promoting plant health using free enzymes and microorganisms that overexpress enzymes SPOGEN BIOTECH INC. (US) 2026-05-19 US disclosed
US-12599141-B2 Rod-shaped plant viral nanoparticles or virus-like particles for agricultural applications CASE WESTERN RESERVE UNIVERSITY (US) 2026-04-14 US disclosed
CN-1013443-B PROCESS FOR PREPARING IMIDAZOLE DERIVATIVES SHIONOGI & CO (JP) 1991-08-07 CN disclosed
US-4629795-A FUNGICIDES SHIONOGI & CO., LTD. (JP) 1986-12-16 US disclosed
EP-0162359-A2 A process for preparing imidazole derivatives SHIONOGI & CO., LTD. (JP) 1985-11-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630484-B2 Methods for promoting plant health using free enzymes and microorganisms that overexpress enzymes ADA, RNGTT, GNPDA1 HTR1A 2601/4885ADORA3 1485/4885TBXA2R 4250/4885
US-12599141-B2 Rod-shaped plant viral nanoparticles or virus-like particles for agricultural applications PRNP, PCNP, VIM HTR1A 1246/4885ADORA3 4377/4885TBXA2R 3685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.