Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5063568 | 0.99 | ITGB3 (0.37) | ITGB3ITGA2BF10FOLH1PTGER4 | |
| SCHEMBL5059296 | 0.79 | ITGB3 (0.52) | ITGB3ITGA2BFOLH1MEN1KMT2A | |
| SCHEMBL3956989 | 0.76 | SLC1A3 (0.47) | FOLH1HTT | |
| Hydrochloric Acid SCHEMBL5063371 | 0.76 | SLC1A3 (0.47) | FOLH1HTT | |
| SCHEMBL3957623 | 0.75 | ITGB3 (0.59) | ITGB3ITGA2BKLK7KLK5 | |
| SCHEMBL3951637 | 0.73 | MAPT (0.51) | ITGB3ITGA2BFOLH1KLK7KLK5 | |
| SCHEMBL13997588 | 0.73 | PADI1 (0.33) | KMT2A | |
| SCHEMBL19665701 | 0.71 | HDAC3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL17646236 | 0.71 | HDAC3 (0.47) | ITGB3ITGA2B | |
| SCHEMBL17646251 | 0.71 | HDAC3 (0.47) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866291-B1 | ANTIBACTERIAL AMIDE MACROCYCLES VI | AICURIS GMBH & CO KG (DE) | 2009-07-15 | — | — | EP | disclosed |