Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957623 | 0.91 | ITGB3 (0.59) | ITGB3ITGA2BNPC1ALDH1A1CYP3A4 | |
| SCHEMBL3957619 | 0.82 | ITGB3 (0.44) | ITGB3ITGA2BDPP8DPP7DPP4 | |
| SCHEMBL3958711 | 0.79 | ITGB3 (0.38) | ITGB3ITGA2BFOLH1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5063568 | 0.78 | ITGB3 (0.37) | ITGB3ITGA2BFOLH1MEN1KMT2A | |
| SCHEMBL10770977 | 0.74 | FOLH1 (0.64) | ITGB3ITGA2BFOLH1ACEMEN1 | |
| SCHEMBL7323375 | 0.73 | FOLH1 (0.66) | ITGB3ITGA2BFOLH1ACE | |
| SCHEMBL1938810 | 0.72 | HTT (0.54) | ITGB3ITGA2BNPC1ALDH1A1CYP3A4 | |
| SCHEMBL1938809 | 0.72 | HTT (0.54) | ITGB3ITGA2BNPC1ALDH1A1CYP3A4 | |
| SCHEMBL10772400 | 0.71 | FOLH1 (0.68) | ITGB3FOLH1ACE | |
| SCHEMBL3951637 | 0.71 | MAPT (0.51) | ITGB3ITGA2BFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080300231-A1 | Antibacterial amide macrocycles VI | BAYER HEALTHCARE AG (DE) | 2008-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300231-A1 | Antibacterial amide macrocycles VI | AADAC, AAAS, NOD2 | ITGB3 4166/4885ITGA2B 4302/4885NPC1 1089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.