SCHEMBL3959658

SCHEMBL3959658

Cc1ccc(OC(=O)c2cccc(C)c2N)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.63
RAB9A P51151 8/20 0.63
SMN1; SMN2 Q16637 6/20 0.63
ALDH1A1 P00352 6/20 0.63
IGF2BP2 Q9Y6M1 1/20 0.60
MAPT P10636 6/20 0.59
HPGD P15428 5/20 0.59
TDP1 Q9NUW8 2/20 0.59
NPSR1 Q6W5P4 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
THRB P10828 1/20 0.58
KDM4E B2RXH2 5/20 0.54
POLB P06746 1/20 0.52
LMNA P02545 2/20 0.46
KMT2A Q03164 2/20 0.46
MEN1 O00255 1/20 0.46
CYP1A2 P05177 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11593721 0.81 IGF2BP2 (0.81) NPC1RAB9ASMN1; SMN2ALDH1A1IGF2BP2
SCHEMBL11339738 0.80 NPC1 (0.74) NPC1RAB9ASMN1; SMN2ALDH1A1IGF2BP2
SCHEMBL563078 0.78 NPC1 (1.00) NPC1RAB9ASMN1; SMN2ALDH1A1IGF2BP2
SCHEMBL28710441 0.75 NPC1 (0.74) NPC1RAB9ASMN1; SMN2ALDH1A1IGF2BP2
SCHEMBL29575333 0.75 NPC1 (0.78) NPC1RAB9ASMN1; SMN2ALDH1A1IGF2BP2
SCHEMBL285733 0.75 NPC1 (0.78) NPC1RAB9ASMN1; SMN2ALDH1A1IGF2BP2
SCHEMBL11691319 0.74 NPC1 (0.58) NPC1RAB9ASMN1; SMN2ALDH1A1IGF2BP2
SCHEMBL11593974 0.74 NPC1 (0.72) NPC1RAB9ASMN1; SMN2ALDH1A1IGF2BP2
SCHEMBL11396153 0.74 NPC1 (0.72) NPC1RAB9ASMN1; SMN2ALDH1A1IGF2BP2
SCHEMBL7086957 0.73 NPC1 (0.70) NPC1RAB9ASMN1; SMN2ALDH1A1IGF2BP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507750-B2 Stabilized ascorbic acid derivative SHOWA DENKO K.K. (JP) 2009-03-24 US disclosed
US-20070141000-A1 STABILIZED ASCORBIC ACID DERIVATIVE SHOWA DENKO K.K. 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070141000-A1 STABILIZED ASCORBIC ACID DERIVATIVE SOD1, PROC, RBP1 NPC1 727/4885RAB9A 453/4885SMN1; SMN2 630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.