Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | PRKACG | P22612 | 1/20 | 0.36 |
| ▸ | PRKACB | P22694 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 6/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960010 | 1.00 | HTR1D (0.40) | HTR1DTDP1KDM4EALOX15APEX1 | |
| Hydrochloric Acid SCHEMBL27740057 | 0.99 | HTR1D (0.39) | HTR1DTDP1KDM4EALOX15APEX1 | |
| Hydrochloric Acid SCHEMBL27740058 | 0.99 | HTR1D (0.39) | HTR1DTDP1KDM4EALOX15APEX1 | |
| SCHEMBL4763284 | 0.92 | HTR1A (0.44) | HTR1DTDP1KDM4EALOX15APEX1 | |
| SCHEMBL4763276 | 0.92 | HTR1A (0.44) | HTR1DTDP1KDM4EALOX15APEX1 | |
| SCHEMBL5423282 | 0.89 | HTR1D (0.39) | HTR1DTDP1KDM4EALOX15APEX1 | |
| SCHEMBL4763248 | 0.89 | HTR1D (0.39) | HTR1DTDP1KDM4EALOX15APEX1 | |
| SCHEMBL28775840 | 0.85 | HTR1A (0.35) | HTR1DTDP1KDM4EALOX15APEX1 | |
| SCHEMBL28775842 | 0.81 | HTR7 (0.33) | HTR1DTDP1KDM4EALOX15APEX1 | |
| SCHEMBL3964423 | 0.80 | HTR7 (0.47) | KDM4EHSD17B10PRKACAPRKACGPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243075-A | Novel 2,3-dihydroindole compounds | LUNDBECK & CO AS H (DK) | 2008-08-13 | — | — | CN | claimed |
| US-7544685-B2 | 2,3-dihydroindole compounds | H. LUNDBECK A/S (DK) | 2009-06-09 | — | — | US | disclosed |
| CN-101243075-A | Novel 2,3-dihydroindole compounds | LUNDBECK & CO AS H (DK) | 2008-08-13 | — | — | CN | disclosed |