Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.51 |
| ▸ | NOS2 | P35228 | 1/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 9/20 | 0.40 |
| ▸ | MMP13 | P45452 | 9/20 | 0.40 |
| ▸ | MMP3 | P08254 | 7/20 | 0.40 |
| ▸ | MMP9 | P14780 | 7/20 | 0.40 |
| ▸ | MMP8 | P22894 | 7/20 | 0.40 |
| ▸ | MMP14 | P50281 | 6/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.40 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GCK | P35557 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3960109 | 0.86 | CCR7 (0.45) | SLC22A12MMP2MMP13MMP3MMP9 | |
| SCHEMBL1464281 | 0.83 | MMP2 (0.51) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL3963998 | 0.83 | GCK (0.45) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL3963859 | 0.79 | MAPT (0.42) | SLC22A12MAPTGAA | |
| SCHEMBL1464260 | 0.78 | MMP2 (0.49) | SLC22A12MMP2MMP13MMP3MMP9 | |
| SCHEMBL1464025 | 0.78 | MMP2 (0.48) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL3963997 | 0.77 | KMT2A (0.60) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL1464356 | 0.75 | MMP2 (0.65) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL3959480 | 0.74 | P2RX7 (0.43) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL3964990 | 0.72 | MMP2 (0.48) | MMP2MMP13MMP3MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |