Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CCR6 | P51684 | 6/20 | 0.50 |
| ▸ | CCR7 | P32248 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 7/20 | 0.40 |
| ▸ | MMP13 | P45452 | 7/20 | 0.40 |
| ▸ | MMP3 | P08254 | 6/20 | 0.40 |
| ▸ | MMP9 | P14780 | 6/20 | 0.40 |
| ▸ | MMP8 | P22894 | 6/20 | 0.40 |
| ▸ | MMP14 | P50281 | 5/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962698 | 0.93 | KMT2A (0.55) | KMT2ACCR6CCR7MAPK1MAPT | |
| SCHEMBL3963998 | 0.86 | GCK (0.45) | KMT2ACCR6MMP2MMP13MMP3 | |
| SCHEMBL3960109 | 0.84 | CCR7 (0.45) | KMT2ACCR6CCR7MMP2MMP13 | |
| SCHEMBL1464281 | 0.83 | MMP2 (0.51) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL3959480 | 0.83 | P2RX7 (0.43) | KMT2AMMP2MMP13MMP3MMP9 | |
| SCHEMBL1464260 | 0.78 | MMP2 (0.49) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL1996711 | 0.78 | KMT2A (1.00) | KMT2ACCR6CCR7MAPK1HSD11B1 | |
| SCHEMBL3963859 | 0.77 | MAPT (0.42) | CCR6CCR7MAPT | |
| SCHEMBL3960112 | 0.77 | NOS3 (0.51) | MMP2MMP13MMP3MMP9MMP8 | |
| SCHEMBL1463903 | 0.76 | MMP2 (0.51) | CCR6MMP2MMP13MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |