Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957933 | 0.84 | HSP90AA1 (0.43) | ADORA3ALDH1A1 | |
| SCHEMBL3963292 | 0.84 | PIK3CD (0.44) | ADORA3 | |
| SCHEMBL3961113 | 0.83 | PDE4A (0.49) | — | |
| SCHEMBL3960757 | 0.83 | CNR2 (0.46) | ADORA3 | |
| SCHEMBL3962706 | 0.83 | SLC29A1 (0.49) | SLC29A1 | |
| SCHEMBL3959345 | 0.82 | SLC29A1 (0.38) | SLC29A1ADORA3P2RX3 | |
| SCHEMBL3958830 | 0.82 | SLC29A1 (0.42) | SLC29A1ADORA3P2RX3 | |
| SCHEMBL3955238 | 0.82 | SLC29A1 (0.42) | SLC29A1ADORA3 | |
| SCHEMBL3957037 | 0.81 | ADORA2A (0.52) | SLC29A1 | |
| SCHEMBL3964379 | 0.81 | GAA (0.45) | ADORA3ALDH1A1GAAP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034386-A1 | DERIVATIVES OF ADENINE AND 8-AZA-ADENINE AND USES THEREOF-796 | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | WO | claimed |
| WO-2009034386-A1 | DERIVATIVES OF ADENINE AND 8-AZA-ADENINE AND USES THEREOF-796 | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | WO | disclosed |