Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3957037 | 0.89 | ADORA2A (0.52) | SLC29A1MEN1KMT2AADORA2AADORA1 | |
| SCHEMBL3959345 | 0.87 | SLC29A1 (0.38) | SLC29A1ADORA2AADORA1 | |
| SCHEMBL3958830 | 0.85 | SLC29A1 (0.42) | SLC29A1 | |
| SCHEMBL3955238 | 0.85 | SLC29A1 (0.42) | SLC29A1 | |
| SCHEMBL3955307 | 0.85 | ADORA2A (0.49) | ADORA2AADORA1 | |
| SCHEMBL3960150 | 0.85 | PDE4A (0.45) | — | |
| SCHEMBL7208530 | 0.84 | PDE4A (0.55) | ADORA2AADORA1 | |
| SCHEMBL3957706 | 0.84 | ALDH1A1 (0.45) | LMNAKMT2A | |
| SCHEMBL3958986 | 0.84 | HSP90AA1 (0.44) | SLC29A1LMNAKMT2A | |
| SCHEMBL3960833 | 0.83 | SLC29A1 (0.40) | SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034386-A1 | DERIVATIVES OF ADENINE AND 8-AZA-ADENINE AND USES THEREOF-796 | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | WO | claimed |
| WO-2009034386-A1 | DERIVATIVES OF ADENINE AND 8-AZA-ADENINE AND USES THEREOF-796 | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | WO | disclosed |