Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958830 | 0.90 | SLC29A1 (0.42) | SLC29A1ADORA3P2RX3 | |
| SCHEMBL3958986 | 0.88 | HSP90AA1 (0.44) | SLC29A1 | |
| SCHEMBL3962706 | 0.87 | SLC29A1 (0.49) | SLC29A1ADORA2AADORA1 | |
| SCHEMBL3958684 | 0.86 | PDE8A (0.43) | ADORA3P2RX3 | |
| SCHEMBL3955318 | 0.84 | ADORA3 (0.42) | ADORA3P2RX3 | |
| SCHEMBL3957037 | 0.84 | ADORA2A (0.52) | SLC29A1ADORA2AADORA1 | |
| SCHEMBL3960757 | 0.82 | CNR2 (0.46) | ADORA3ADORA2A | |
| SCHEMBL3960833 | 0.82 | SLC29A1 (0.40) | SLC29A1ADORA3P2RX3 | |
| SCHEMBL3957933 | 0.80 | HSP90AA1 (0.43) | ADORA3 | |
| SCHEMBL3963832 | 0.80 | PDE4A (0.43) | ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034386-A1 | DERIVATIVES OF ADENINE AND 8-AZA-ADENINE AND USES THEREOF-796 | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | WO | claimed |
| WO-2009034386-A1 | DERIVATIVES OF ADENINE AND 8-AZA-ADENINE AND USES THEREOF-796 | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | WO | disclosed |