SCHEMBL396114

SCHEMBL396114

C=C(Cc1ccccc1NS(=O)(=O)CC)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSIP1 O75475 1/20 0.47
KCNA5 P22460 1/20 0.44
HPGD P15428 3/20 0.43
LMNA P02545 1/20 0.43
NR3C1 P04150 1/20 0.40
PTGS2 P35354 3/20 0.39
ALDH1A1 P00352 3/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.38
GAA P10253 1/20 0.38
GFER P55789 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 1/20 0.38
PTGS1 P23219 1/20 0.37
CXCL8 P10145 2/20 0.37
NR3C2 P08235 1/20 0.37
MRGPRX1 Q96LB2 2/20 0.37
POLB P06746 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL398054 0.87 KMT2A (0.48) HPGDNR3C1ALDH1A1KDM4EGAA
SCHEMBL398529 0.82 KMT2A (0.47) LMNAALDH1A1KDM4EMAPTMEN1
SCHEMBL2046750 0.80 MEN1 (0.44) HPGDPTGS2ALDH1A1KDM4EMAPT
SCHEMBL396513 0.80 LMNA (0.54) KCNA5LMNAALDH1A1KDM4EMAPT
SCHEMBL10379711 0.78 PSIP1 (0.49) PSIP1KCNA5HPGDLMNANR3C1
SCHEMBL6493990 0.77 POLB (0.50) HPGDLMNAPTGS2ALDH1A1KDM4E
SCHEMBL7336703 0.76 AKR1B1 (0.41) PTGS2ALDH1A1MAPT
SCHEMBL8746636 0.75 AKR1B1 (0.46) HPGDLMNAALDH1A1KDM4EMAPT
SCHEMBL3553627 0.73 SLC16A3 (0.50) PSIP1KCNA5HPGDLMNA
SCHEMBL12768022 0.73 PSIP1 (0.73) PSIP1KCNA5HPGDLMNANR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed