SCHEMBL398529

SCHEMBL398529

C=C(Cc1ccccc1NS(=O)(=O)c1ccccc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.47
ALDH1A1 P00352 3/20 0.47
TSHR P16473 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 3/20 0.46
POLB P06746 1/20 0.46
RECQL P46063 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
SLC16A3 O15427 1/20 0.44
PTGDR2 Q9Y5Y4 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
MAPK1 P28482 1/20 0.43
HTT P42858 1/20 0.43
METAP2 P50579 1/20 0.43
MMP2 P08253 1/20 0.43
MCL1 Q07820 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396513 0.91 LMNA (0.54) KMT2AALDH1A1TSHRKDM4EMEN1
SCHEMBL5205026 0.84 ALDH1A1 (0.58) KMT2AALDH1A1TSHRKDM4EMEN1
SCHEMBL398054 0.84 KMT2A (0.48) KMT2AALDH1A1TSHRKDM4ESMN1; SMN2
SCHEMBL396114 0.82 PSIP1 (0.47) KMT2AALDH1A1TSHRKDM4EMEN1
SCHEMBL27478563 0.78 ALDH1A1 (0.53) KMT2AALDH1A1TSHRKDM4EMEN1
SCHEMBL12050285 0.78 RECQL (0.57) KMT2AALDH1A1TSHRKDM4EMEN1
SCHEMBL397676 0.77 HDAC1 (0.68) KMT2AALDH1A1MEN1POLBLMNA
SCHEMBL10272404 0.76 ALDH1A1 (0.71) KMT2AALDH1A1TSHRPOLBRECQL
SCHEMBL3897238 0.76 KEAP1 (0.55) KMT2AALDH1A1TSHRKDM4EPOLB
SCHEMBL7866143 0.75 LMNA (0.59) KMT2AALDH1A1TSHRKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed