Phenoxazine

Phenoxazine

SCHEMBL3961176

c1ccc2c(c1)Nc1ccccc1O2.c1ccc2nc3ccccc3nc2c1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 8/20 0.74
DHODH Q02127 1/20 0.65
NOX1 Q9Y5S8 1/20 0.50
MAPT P10636 4/20 0.48
GAA P10253 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
HTR2B P41595 2/20 0.40
HTR7 P34969 1/20 0.40
NQO2 P16083 1/20 0.39
LMNA P02545 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenoxazine SCHEMBL28350911 0.91 ALOX5 (0.61) ALOX5DHODHNOX1MAPTGAA
Phenoxazine SCHEMBL27458642 0.88 ALOX5 (0.63) ALOX5DHODHNOX1MAPTGAA
Phenoxazine SCHEMBL28263385 0.88 ALOX5 (0.57) ALOX5DHODHNOX1MAPTMEN1
Phenoxazine SCHEMBL7862 0.86 ALOX5 (1.00) ALOX5DHODHMAPTGAANPSR1
Phenoxazine SCHEMBL28844098 0.86 ALOX5 (1.00) ALOX5DHODHMAPTGAANPSR1
Phenoxazine SCHEMBL29355714 0.86 ALOX5 (1.00) ALOX5DHODHMAPTGAANPSR1
Phenoxazine SCHEMBL6310178 0.86 ALOX5 (1.00) ALOX5DHODHMAPTGAANPSR1
Phenoxazine SCHEMBL18770789 0.84 ALOX5 (0.85) ALOX5DHODHMAPTGAANPSR1
Phenoxazine SCHEMBL25275195 0.84 ALOX5 (0.94) ALOX5DHODHMAPTGAANPSR1
Phenoxazine SCHEMBL5808288 0.84 ALOX5 (0.94) ALOX5DHODHMAPTGAANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113801102-A Phenazinyl-based compound and preparation method and application thereof 上海交通大学 2021-12-17 CN disclosed
CN-107428709-B Cationic direct dyes 巴斯夫欧洲公司 2021-10-08 CN disclosed
CN-103204996-A Organic electroluminescent device MERCK PATENT GMBH 2013-07-17 CN disclosed
CN-101171320-B Organic electroluminescent device MERCK PATENT GMBH 2013-04-10 CN disclosed
US-8323804-B2 Partially conjugated polymers, their representation and their use MERCK PATENT GMBH (DE) 2012-12-04 US disclosed
CN-101155896-B Organic electroluminescent device MERCK PATENT GMBH 2012-08-29 CN disclosed
CN-101142294-B Novel materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2011-12-07 CN disclosed
CN-101600777-A The type material that is used for organic electroluminescence device MERCK PATENT GMBH (DE) 2009-12-09 CN disclosed
US-20090226759-A1 Partially Conjugated Polymers, Their Representation and Their Use MERCK PATENT GMBH (DE) 2009-09-10 US disclosed
EP-2079313-A2 ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND METHODS FOR THEIR USE Oligos Etc. Inc. (US) 2009-07-22 EP disclosed
WO-2008133704-A2 ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND METHODS FOR THEIR USE OLIGOS ETC., INC. (US) 2008-11-06 WO disclosed
CN-101171320-A Organic electroluminescent device MERCK PATENT GMBH (DE) 2008-04-30 CN disclosed
CN-101155896-A Organic electroluminescent device MERCK PATENT GMBH (DE) 2008-04-02 CN disclosed
CN-101142294-A Novel materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2008-03-12 CN disclosed
EP-1667947-A1 METHODS OF 11C -RADIOLABELLING PHENOTHIAZINE AND PHENO THIAZINE-LIKE COMPOUNDS The University Court of the University of Aberdeen (GB) 2006-06-14 EP disclosed
WO-2005030676-A1 METHODS OF [11C]-RADIOLABELLING PHENOTHIAZINE AND PHENOTHIAZINE-LIKE COMPOUNDS THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN (GB) 2005-04-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090226759-A1 Partially Conjugated Polymers, Their Representation and Their Use MAP1LC3B, PARG, MAP1LC3C ALOX5 2100/4885DHODH 1565/4885NOX1 1160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.