Phenoxazine

Phenoxazine

SCHEMBL28263385

c1ccc2c(c1)Nc1ccccc1O2.c1ccc2cc3cc4nc5ccccc5nc4cc3cc2c1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 7/20 0.57
NQO2 P16083 3/20 0.53
DHODH Q02127 1/20 0.53
MAPT P10636 4/20 0.41
ALDH1A1 P00352 2/20 0.41
GLA P06280 1/20 0.41
HPGD P15428 1/20 0.41
ACHE P22303 1/20 0.41
NOX1 Q9Y5S8 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 2/20 0.37
NPC1 O15118 2/20 0.37
POLB P06746 2/20 0.37
KMT2A Q03164 2/20 0.37
USP2 O75604 1/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
HTR2B P41595 2/20 0.37
HTR7 P34969 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenoxazine SCHEMBL28350911 0.90 ALOX5 (0.61) ALOX5NQO2DHODHMAPTALDH1A1
Phenoxazine SCHEMBL27458642 0.88 ALOX5 (0.63) ALOX5NQO2DHODHMAPTALDH1A1
Phenoxazine SCHEMBL3961176 0.88 ALOX5 (0.74) ALOX5NQO2DHODHMAPTALDH1A1
Phenoxazine SCHEMBL6846406 0.86 ALOX5 (0.77) ALOX5DHODHMAPTALDH1A1NOX1
Phenoxazine SCHEMBL18770789 0.78 ALOX5 (0.85) ALOX5DHODHMAPTALDH1A1L3MBTL1
SCHEMBL13156494 0.78 NQO2 (0.89) NQO2MAPTALDH1A1GLAHPGD
SCHEMBL30779382 0.77 ALOX5 (0.68) ALOX5DHODHMAPTALDH1A1NOX1
SCHEMBL302837 0.77 ALOX5 (0.68) ALOX5DHODHMAPTALDH1A1NOX1
Phenoxazine SCHEMBL29355714 0.75 ALOX5 (1.00) ALOX5DHODHMAPTALDH1A1L3MBTL1
Phenoxazine SCHEMBL28844098 0.75 ALOX5 (1.00) ALOX5DHODHMAPTALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107068877-B A kind of organic electroluminescence device of the anthraquinone analog compound containing 9,10- and its application 中节能万润股份有限公司 2018-12-28 CN disclosed