Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323737 | 0.77 | LDHA (0.39) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL19962980 | 0.74 | MAOB (0.39) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL19962979 | 0.74 | MAOB (0.39) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL3756550 | 0.73 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL3750536 | 0.73 | NQO1 (0.50) | FFAR1MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL473959 | 0.70 | CA12 (0.43) | MEN1KMT2AALDH1A1SLC6A4HTR1A | |
| SCHEMBL30193796 | 0.70 | CA12 (0.43) | MEN1KMT2AALDH1A1SLC6A4HTR1A | |
| SCHEMBL4185405 | 0.70 | APP (0.37) | SLC6A4 | |
| SCHEMBL27172043 | 0.70 | KDM4E (0.36) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL19951530 | 0.70 | PRKAB2 (0.44) | MEN1KMT2AALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009030871-A1 | PYRROLOPYRIMIDINE DERIVATIVES HAVING HSP90 INHIBITORY ACTIVITY | VERNALIS R & D LTD (GB) | 2009-03-12 | — | — | WO | disclosed |