Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.51 |
| ▸ | IGF1R | P08069 | 2/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.51 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.51 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 5/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6242523 | 0.85 | CNOT7 (0.51) | THRBP2RX7SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9741417 | 0.84 | BTK (0.50) | THRBMCHR1P2RX7HIF1A | |
| SCHEMBL11452514 | 0.83 | THRB (0.55) | NTRK1IGF1RFGFR1NTRK2NTRK3 | |
| SCHEMBL11452735 | 0.82 | THRB (0.46) | THRB | |
| SCHEMBL11454232 | 0.81 | THRB (0.45) | THRBNPBWR1MCHR1P2RX7NPSR1 | |
| SCHEMBL9380739 | 0.79 | CYP1A2 (0.50) | CYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL11784925 | 0.78 | HTR6 (0.43) | THRBP2RX7NPSR1ALDH1A1LMNA | |
| SCHEMBL11452562 | 0.77 | THRB (0.80) | THRBP2RX7LMNA | |
| SCHEMBL7909905 | 0.76 | KMT2A (0.58) | THRBNPBWR1P2RX7SMN1; SMN2ALDH1A1 | |
| SCHEMBL30174384 | 0.76 | THRB (0.46) | THRBNPBWR1P2RX7CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079715-A1 | TRIAZINES AND THEIR USE AS INHIBITORS OF METALLOPROTEINASES | TSSCHESCHE, Harald (DE) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008046657-A1 | TRIAZINES AND THEIR USE AS INHIBITORS OF METALLOPROTEINASES | TSSCHESCHE HARALD (DE) | 2008-04-24 | — | — | WO | disclosed |