Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962079 | 0.85 | NTRK1 (0.51) | HIF1AALDH1A1SMN1; SMN2LMNANPSR1 | |
| SCHEMBL11784925 | 0.84 | HTR6 (0.43) | CNOT7HIF1AALDH1A1HTTLMNA | |
| SCHEMBL30174384 | 0.81 | THRB (0.46) | RAB9AALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL7909905 | 0.81 | KMT2A (0.58) | RAB9AALDH1A1NPC1SMN1; SMN2LMNA | |
| SCHEMBL30174385 | 0.81 | MEN1 (0.47) | RAB9AALDH1A1HTTNPC1MAPT | |
| SCHEMBL10512600 | 0.81 | HIF1A (0.50) | HIF1ATHRBP2RX7MEN1NR1I2 | |
| SCHEMBL10670742 | 0.81 | P2RX7 (0.43) | CNOT7HIF1ARAB9AALDH1A1HTT | |
| SCHEMBL10439328 | 0.80 | MAPK14 (0.45) | ALDH1A1HTTMAPTSMN1; SMN2LMNA | |
| SCHEMBL3582300 | 0.80 | TSHR (0.42) | DDB1CRBNRAB9ANPC1MAPT | |
| SCHEMBL10439124 | 0.80 | NPC1 (0.55) | RAB9AALDH1A1HTTNPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583919-A | Preparation method of 6-oxyalkyl 1,2,4-triazine-3,5 (2H, 4H) -diketone derivative | 河北工业大学 | 2023-01-10 | — | — | CN | claimed |
| CN-113248454-B | Method for preparing 2- [ phenyl ] -1,2, 4-triazine-3, 5(2H,4H) -diketone compound | 山东国邦药业有限公司 | 2021-09-24 | — | — | CN | claimed |
| CN-113248454-A | Method for preparing 2- [ phenyl ] -1,2, 4-triazine-3, 5(2H,4H) -diketone compound | 山东国邦药业有限公司 | 2021-08-13 | — | — | CN | claimed |
| US-4198407-A | Substituted 2-phenyl-1,2,4-triazine-3,5(2H,4H)-diones, and coccidiostatic agents containing same | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-15 | — | — | US | claimed |
| WO-2026067791-A1 | 2-PHENYL-1,2,4-TRIAZINE-3,5(2H,4H)-DIONE DERIVATIVES AS THR-BETA AGONIST OR MODULATORS FOR THE TREATMENT OF OBESITY | ASCLETIS PHARMA (CHINA) CO., LIMITED (CN) | 2026-04-02 | — | — | WO | disclosed |
| CN-115583919-B | Preparation method of 6-oxyalkyl 1,2, 4-triazine-3, 5 (2H, 4H) -diketone derivative | 河北工业大学 | 2024-04-19 | — | — | CN | disclosed |
| EP-4240730-A1 | 2-PYRIDONES AS THYROID HORMONE RECEPTOR MODULATORS | Aligos Therapeutics, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| EP-4240737-A2 | BICYCLIC PYRIDAZINONES AS THYROID HORMONE RECEPTOR BETA (TR-BETA) AGONISTS | Aligos Therapeutics, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| CN-115583919-A | Preparation method of 6-oxyalkyl 1,2,4-triazine-3,5 (2H, 4H) -diketone derivative | 河北工业大学 | 2023-01-10 | — | — | CN | disclosed |
| WO-2022099044-A1 | 2-PYRIDONES AS THYROID HORMONE RECEPTOR MODULATORS | ALIGOS THERAPEUTICS, INC. (US) | 2022-05-12 | — | — | WO | disclosed |
| WO-2022099060-A2 | BICYCLIC PYRIDAZINONES AND METHODS OF USE THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2022-05-12 | — | — | WO | disclosed |
| CN-113248454-B | Method for preparing 2- [ phenyl ] -1,2, 4-triazine-3, 5(2H,4H) -diketone compound | 山东国邦药业有限公司 | 2021-09-24 | — | — | CN | disclosed |
| EP-0170316-A2 | alpha-Aryl-4-(4,5-dihydro-3,5-dioxo-1,2,4-triazin-2(3H)-yl)benzeneacetonitriles | JANSSEN PHARMACEUTICA N.V. (BE) | 1986-02-05 | — | — | EP | disclosed |
| US-4198407-A | Substituted 2-phenyl-1,2,4-triazine-3,5(2H,4H)-diones, and coccidiostatic agents containing same | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-15 | — | — | US | disclosed |
| US-4198407-A | Substituted 2-phenyl-1,2,4-triazine-3,5(2H,4H)-diones, and coccidiostatic agents containing same | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-15 | — | — | US | disclosed |
| US-4198407-A | Substituted 2-phenyl-1,2,4-triazine-3,5(2H,4H)-diones, and coccidiostatic agents containing same | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-15 | — | — | US | disclosed |
| US-3970752-A | Coccidiocidal compositions utilizing 1-phenyl-substituted 1,3,5-triazine | BAYER AKTIENGESELLSCHAFT (DT) | 1976-07-20 | — | — | US | disclosed |
| US-3948893-A | COCCIDIOSIS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-06 | — | — | US | disclosed |
| US-3912723-A | 2-Phenyl-as-triazine-3,5(2H,4H)diones | PFIZER | 1975-10-14 | — | — | US | disclosed |
| US-3905971-A | 2-Phenyl-as-triazine-3,5(2H,4H)diones | PFIZER | 1975-09-16 | — | — | US | disclosed |