Lactic Acid

Lactic Acid

SCHEMBL3962098

CC(O)C(=O)O.c1cc2cc-2c1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1

The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 known ✓ P35462 1/20 0.41
TP53 P04637 1/20 0.52
PTGS2 P35354 7/20 0.49
KMO O15229 1/20 0.48
RXRA P19793 2/20 0.47
RXRB P28702 2/20 0.47
RXRG P48443 1/20 0.47
CYP1A2 P05177 1/20 0.42
GAA P10253 1/20 0.42
CYP2C9 P11712 1/20 0.42
PKM P14618 1/20 0.42
CYP2C19 P33261 1/20 0.42
ACMSD Q8TDX5 1/20 0.42
PTPN1 P18031 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ESR1 P03372 1/20 0.41
MGLL Q99685 1/20 0.41
PTGS1 P23219 2/20 0.41
FABP2 P12104 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lactic Acid SCHEMBL11565204 0.89 TP53 (0.46) TP53PTGS2KMORXRARXRB
SCHEMBL3478959 0.88 KMO (0.50) PTGS2KMORXRARXRBRXRG
SCHEMBL27652732 0.85 KMO (0.52) PTGS2KMORXRARXRBRXRG
Biphenyl SCHEMBL27473317 0.85 PTGS2 (0.61) TP53PTGS2CYP1A2GAACYP2C9
Alanine SCHEMBL4261908 0.84 TAAR1 (0.47) PTGS2KMORXRARXRBRXRG
SCHEMBL8927749 0.84 KMO (0.47) PTGS2KMORXRARXRBRXRG
Lactic Acid SCHEMBL11570987 0.82 KMO (0.72) KMORXRARXRBRXRGGAA
Isopropyl Alcohol SCHEMBL6748246 0.82 MEN1 (0.50) PTGS2KMORXRARXRBRXRG
Threonine SCHEMBL1882390 0.81 PTGS2 (0.43) PTGS2KMORXRARXRBRXRG
SCHEMBL29152365 0.80 PTGS2 (0.50) PTGS2KMORXRARXRBRXRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009040829-A1 A NOVEL PROCESS FOR THE PREPARATION OF DOCETAXEL BENZOCHEM LIFESCIENCE (P) LIMITED (IN) 2009-04-02 WO claimed
CN-122081969-A VSe-Cu2-xSe nanosheet catalysis C (sp)3) -H bond CO2Method for directionally synthesizing alpha-hydroxy/amino acid by carboxylation 2026-05-26 CN disclosed
WO-2003024915-A1 A PROCESS FOR THE PREPARATION OF 3-ARYL-2-HYDROXY PROPANOIC ACID DERIVATIVES DR. REDDY'S LABORATORIES LTD. (IN) 2003-03-27 WO disclosed
WO-2003024915-A1 A PROCESS FOR THE PREPARATION OF 3-ARYL-2-HYDROXY PROPANOIC ACID DERIVATIVES DR. REDDY'S LABORATORIES LTD. (IN) 2003-03-27 WO disclosed
EP-0054862-A1 Substituted dipeptides, processes for their preparation and pharmaceutical compositions containing them and their use in the inhibition of enkephalinase SCHERING CORPORATION (US) 1982-06-30 EP disclosed