Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CCR6 | P51684 | 4/20 | 0.47 |
| ▸ | CCR7 | P32248 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963997 | 0.93 | KMT2A (0.60) | KMT2ACCR6CCR7MAPTMAPK1 | |
| SCHEMBL3963859 | 0.84 | MAPT (0.42) | CCR6CCR7MAPTALDH1A1HTT | |
| SCHEMBL3963998 | 0.80 | GCK (0.45) | KMT2ACCR6 | |
| SCHEMBL3960109 | 0.78 | CCR7 (0.45) | KMT2ACCR6CCR7MAPTALDH1A1 | |
| SCHEMBL1464996 | 0.78 | MAPT (0.54) | MAPTALDH1A1HTT | |
| SCHEMBL1464281 | 0.77 | MMP2 (0.51) | MAPT | |
| SCHEMBL3959480 | 0.77 | P2RX7 (0.43) | KMT2AMAPT | |
| SCHEMBL351726 | 0.76 | EEF2K (0.58) | MAPTALDH1A1HTT | |
| SCHEMBL1996711 | 0.74 | KMT2A (1.00) | KMT2ACCR6CCR7HTTMAPK1 | |
| SCHEMBL3959595 | 0.72 | CNR1 (0.47) | MAPTALDH1A1HTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |