Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.46 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986989 | 0.78 | ALDH1A1 (0.50) | SMN1; SMN2DDB1CRBNCOMTALDH1A1 | |
| SCHEMBL8018398 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2DDB1CRBNCOMTALDH1A1 | |
| SCHEMBL6557234 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2DDB1CRBNCOMTALDH1A1 | |
| SCHEMBL6226538 | 0.76 | SMN1; SMN2 (0.48) | SMN1; SMN2DDB1CRBNCOMTALDH1A1 | |
| SCHEMBL14797462 | 0.75 | DDB1 (0.52) | SMN1; SMN2DDB1CRBNCOMTALDH1A1 | |
| SCHEMBL7084389 | 0.72 | SMN1; SMN2 (0.44) | SMN1; SMN2DDB1CRBNCOMTALDH1A1 | |
| SCHEMBL7521304 | 0.71 | KMT2A (0.41) | SMN1; SMN2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8013278 | 0.71 | SMN1; SMN2 (0.43) | SMN1; SMN2DDB1CRBNCOMTALDH1A1 | |
| SCHEMBL30272686 | 0.71 | HPGD (0.50) | SMN1; SMN2DDB1CRBNALDH1A1HPGD | |
| SCHEMBL7768522 | 0.69 | SMN1; SMN2 (1.00) | SMN1; SMN2DDB1CRBNCOMTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095028-B1 | SUBSTITUTED ACYLAMINO PHENYL URACILS | BAYER CROPSCIENCE AG (DE) | 2005-09-07 | — | — | EP | claimed |
| CN-1128791-C | Substituted acylamino phenyl uracils | BAYER AG (DE) | 2003-11-26 | — | — | CN | claimed |
| CN-1121394-C | Substituted phenyluracils | BAYER AG (DE) | 2003-09-17 | — | — | CN | claimed |
| US-6617281-B1 | Substituted acylamino phenyl uracils | BAYER AKTIENGESELLSCHAFT (DE) | 2003-09-09 | — | — | US | claimed |
| CN-1109676-C | Substituted aminophenyluracils as herbicides and insecticides | BAYER AG (DE) | 2003-05-28 | — | — | CN | claimed |
| US-6455697-B2 | Substituted phenyluracils | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-24 | — | — | US | claimed |
| EP-0843667-B1 | SUBSTITUTED PHENYLURACILS | BAYER AG (DE) | 2001-10-17 | — | — | EP | claimed |
| CN-1308615-A | Substituted acylamino phenyl uracils | BAYER AG (DE) | 2001-08-15 | — | — | CN | claimed |
| US-20010003732-A1 | 1-(4-cyano-2-fluoro-5-(2-chloro-2-methoxycarbonylethyl) -phenyl)-3,6-dihydro-2,6-dioxo-3-methyl-4-trifluoromethyl-1-(2H)-pyrimidine, for example; use as herbicides; chemical intermediates and method of synthesis | ANDREE ROLAND (DE) | 2001-06-14 | — | — | US | claimed |
| EP-1095028-A1 | SUBSTITUTED ACYLAMINO PHENYL URACILS | BAYER AG (DE) | 2001-05-02 | — | — | EP | claimed |
| EP-0906290-A1 | SUBSTITUTED PHENYL URACILS AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1999-04-07 | — | — | EP | claimed |
| CN-1197455-A | Substituted phenyluracils | BAYER AG (DE) | 1998-10-28 | — | — | CN | claimed |
| CN-1189157-A | Substituted aminophenyluracils as herbicides and insecticides | BAYER AG (DE) | 1998-07-29 | — | — | CN | claimed |
| EP-0843667-A1 | SUBSTITUTED PHENYLURACILS | BAYER AG (DE) | 1998-05-27 | — | — | EP | claimed |
| EP-0835247-A1 | SUBSTITUTED CARBONYLAMINOPHENYLURACILS | BAYER AG (DE) | 1998-04-15 | — | — | EP | claimed |
| EP-0827497-A1 | SUBSTITUTED AMINOPHENYLURACILS AS HERBICIDES AND INSECTICIDES | BAYER AG (DE) | 1998-03-11 | — | — | EP | claimed |
| WO-1997042176-A1 | SUBSTITUTED PHENYL URACILS AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-11-13 | — | — | WO | claimed |
| WO-1997005118-A1 | SUBSTITUTED PHENYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-13 | — | — | WO | claimed |
| WO-1997001542-A1 | SUBSTITUTED CARBONYLAMINOPHENYLURACILS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | claimed |
| WO-1996035679-A1 | SUBSTITUTED AMINOPHENYLURACILS AS HERBICIDES AND INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-14 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010003732-A1 | 1-(4-cyano-2-fluoro-5-(2-chloro-2-methoxycarbonylethyl) -phenyl)-3,6-dihydro-2,6-dioxo-3-methyl-4-trifluoromethyl-1-(2H)-pyrimidine, for example; use as herbicides; chemical intermediates and method of synthesis | DDT, DPYD, DHFR | SMN1; SMN2 3660/4885DDB1 212/4885CRBN 2721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.