Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | COMT | P21964 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16364510 | 0.80 | GSK3A (0.43) | ALDH1A1CYP1A2KDM4EGSK3AGSK3B | |
| SCHEMBL6226538 | 0.78 | SMN1; SMN2 (0.48) | ALDH1A1CYP1A2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL6557234 | 0.78 | SMN1; SMN2 (0.48) | ALDH1A1CYP1A2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL3962760 | 0.78 | SMN1; SMN2 (0.53) | ALDH1A1CYP1A2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL8018398 | 0.78 | SMN1; SMN2 (0.48) | ALDH1A1CYP1A2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL14797462 | 0.77 | DDB1 (0.52) | ALDH1A1CYP1A2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL7133435 | 0.77 | GSK3A (0.48) | ALDH1A1CYP1A2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL143175 | 0.75 | ALDH1A1 (0.54) | ALDH1A1CYP1A2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL27577843 | 0.73 | SMN1; SMN2 (0.49) | ALDH1A1CYP1A2SMN1; SMN2HPGDKDM4E | |
| SCHEMBL7084389 | 0.73 | SMN1; SMN2 (0.44) | ALDH1A1CYP1A2SMN1; SMN2HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | JOHNSON & JOHNSON SURGICAL VISION INC (US) | 2023-08-31 | — | — | US | disclosed |
| CN-1481369-A | Substituted phenyluracils compound | �ݶ�ũ�����ѧ�ɷݹ�˾ | 2004-03-10 | — | — | CN | disclosed |
| EP-1330443-A1 | SUBSTITUTED PHENYLURACILS | Bayer CropScience AG (DE) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002034725-A1 | SUBSTITUTED PHENYLURACILS | BAYER CROPSCIENCE AG (DE) | 2002-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230273455-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, PDE6A, PDE6D | ALDH1A1 311/4885CYP1A2 2846/4885SMN1; SMN2 4518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.