Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29594708 | 1.00 | RIPK1 (0.47) | RIPK1PDE5AIDO1ALDH1A1HPGD | |
| SCHEMBL2592408 | 0.88 | TDP1 (0.44) | RIPK1PDE5AALDH1A1L3MBTL1MMP2 | |
| SCHEMBL29693684 | 0.80 | PTPRC (0.50) | RIPK1PDE5AIDO1ALDH1A1HPGD | |
| SCHEMBL3434698 | 0.80 | PTPRC (0.50) | RIPK1PDE5AIDO1ALDH1A1HPGD | |
| SCHEMBL19475174 | 0.78 | ALDH1A1 (0.54) | IDO1ALDH1A1HPGDHSD17B10L3MBTL1 | |
| SCHEMBL3962961 | 0.78 | NPC1 (0.48) | RIPK1PDE5AIDO1ALDH1A1HPGD | |
| SCHEMBL20041412 | 0.78 | L3MBTL1 (0.44) | L3MBTL1SMN1; SMN2KDM4ENPC1CYP3A4 | |
| SCHEMBL30777260 | 0.78 | PTPRC (0.48) | RIPK1PDE5AIDO1ALDH1A1HPGD | |
| SCHEMBL16196249 | 0.78 | MKNK1 (0.47) | RIPK1PDE5AIDO1ALDH1A1HPGD | |
| SCHEMBL4446669 | 0.78 | MKNK1 (0.46) | RIPK1PDE5AIDO1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112010906-B | Bisphosphite and preparation method and application thereof | 中国海洋石油集团有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-112010906-A | Bisphosphite and preparation method and application thereof | 中国海洋石油集团有限公司 | 2020-12-01 | — | — | CN | claimed |
| WO-2022041617-A1 | DIPHOSPHITE, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国海洋石油集团有限公司 | 2022-03-03 | — | — | WO | disclosed |
| CN-112010906-B | Bisphosphite and preparation method and application thereof | 中国海洋石油集团有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-112010906-A | Bisphosphite and preparation method and application thereof | 中国海洋石油集团有限公司 | 2020-12-01 | — | — | CN | disclosed |