Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM5A | P29375 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | PPARD | Q03181 | 7/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1667458 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM5ACES2CES1GPR84 | |
| SCHEMBL31528799 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM5ACES2CES1GPR84 | |
| SCHEMBL20276417 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM5ACES2CES1GPR84 | |
| SCHEMBL15056776 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM5ACES2CES1GPR84 | |
| SCHEMBL2304549 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM5ACES2CES1GPR84 | |
| SCHEMBL8142273 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM5ACES2CES1GPR84 | |
| SCHEMBL14752730 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM5ACES2CES1GPR84 | |
| SCHEMBL1713084 | 0.98 | ALDH1A1 (0.52) | ALDH1A1KDM5ACES2CES1GPR84 | |
| SCHEMBL211903 | 0.91 | ALDH1A1 (0.60) | ALDH1A1KDM5ACES2CES1DNM1 | |
| SCHEMBL29991123 | 0.91 | ALDH1A1 (0.41) | ALDH1A1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3548087-A1 | NUCLEOSIDE TRIPHOSPHATE AND NUCLEOSIDE TRIPHOSPHATE ANALOGUE PRODRUGS | Universität Hamburg (DE) | 2019-10-09 | — | — | EP | disclosed |
| WO-2018100137-A1 | NUCLEOSIDE TRIPHOSPHATE AND NUCLEOSIDE TRIPHOSPHATE ANALOGUE PRODRUGS | UNIVERSITÄT HAMBURG (DE) | 2018-06-07 | — | — | WO | disclosed |
| WO-2018100137-A1 | NUCLEOSIDE TRIPHOSPHATE AND NUCLEOSIDE TRIPHOSPHATE ANALOGUE PRODRUGS | UNIVERSITÄT HAMBURG (DE) | 2018-06-07 | — | — | WO | disclosed |
| US-20090270421-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-10-29 | — | — | US | disclosed |
| US-7560570-B2 | Inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-07-14 | — | — | US | disclosed |
| US-20050239785-A1 | Inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-10-27 | — | — | US | disclosed |
| US-6891043-B2 | Inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-05-10 | — | — | US | disclosed |
| US-20030092734-A1 | Inhibitors of fatty acid amide hydrolase | THE SCRIPPS RESEARCH INSTITUTE | 2003-05-15 | — | — | US | disclosed |
| US-6462054-B1 | ALPHA KETO HETEROCYCLIC PHARMACOPHORE; COMPLEMENTARY BINDING BY ELECTROPHILIC CARBONYL AND WEAKLY BASIC NITROGEN OF SUCH AS OXAZOLOPYRIDINE GROUP; SLEEP AIDS OR ANALGESICS; PRESERVING ENDOGENOUS LEVELS OF OLEAMIDE AND ANANDAMIDE | THE SCRIPPS RESEARCH INSTITUTE | 2002-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270421-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, CNR2 | ALDH1A1 1146/4885KDM5A 359/4885CES2 170/4885 |
| US-20030092734-A1 | Inhibitors of fatty acid amide hydrolase | FAAH, FAAH2, CNR2 | ALDH1A1 859/4885KDM5A 227/4885CES2 110/4885 |
| US-20050239785-A1 | Inhibitors of fatty acid amide hydrolase | FAAH, FAAH2, CNR2 | ALDH1A1 1146/4885KDM5A 359/4885CES2 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.