Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3959908 | 0.86 | ALDH1A1 (0.54) | LDHAGAAALDH1A1LMNAHTT | |
| SCHEMBL30049382 | 0.77 | GAA (0.74) | CA5ALDHAGAANPSR1ALDH1A1 | |
| SCHEMBL153055 | 0.77 | GAA (0.74) | CA5ALDHAGAANPSR1ALDH1A1 | |
| SCHEMBL10948188 | 0.76 | LMNA (0.56) | CA5ALDHAGAANPSR1ALDH1A1 | |
| SCHEMBL27952523 | 0.76 | GAA (0.72) | CA5ALDHAGAANPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2530820 | 0.76 | GAA (0.72) | CA5ALDHAGAANPSR1ALDH1A1 | |
| SCHEMBL3959911 | 0.75 | LDHA (0.51) | CA5ALDHAGAANPSR1ALDH1A1 | |
| SCHEMBL10594988 | 0.74 | ALDH1A1 (0.52) | LDHANPSR1ALDH1A1LMNAHTT | |
| SCHEMBL1515840 | 0.74 | LMNA (0.54) | CA5ALDHAGAANPSR1ALDH1A1 | |
| SCHEMBL11003187 | 0.74 | APP (0.55) | LDHAGAANPSR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079708-A2 | ACYL AMINOIMIDAZOLES AND ACYL AMINOTHIAZOLES | Bayer HealthCare AG (DE) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008043533-A2 | ACYL AMINOIMIDAZOLES AND ACYL AMINOTHIAZOLES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-04-17 | — | — | WO | disclosed |
| WO-2008043533-A2 | ACYL AMINOIMIDAZOLES AND ACYL AMINOTHIAZOLES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-04-17 | — | — | WO | disclosed |
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |