Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8240374 | 1.00 | KDM2B (0.55) | KDM2BNPSR1MGLLMEN1LMNA | |
| SCHEMBL4777663 | 0.84 | MGLL (0.47) | MGLLLMNAKMT2A | |
| SCHEMBL11023752 | 0.83 | SLC6A2 (0.42) | KDM2BL3MBTL1 | |
| SCHEMBL953570 | 0.83 | NPSR1 (0.59) | KDM2BNPSR1MGLLMEN1KMT2A | |
| SCHEMBL16409435 | 0.83 | KDM2B (0.69) | KDM2BNPSR1MGLLMEN1KMT2A | |
| SCHEMBL31375622 | 0.83 | KDM2B (0.69) | KDM2BNPSR1MGLLMEN1KMT2A | |
| SCHEMBL3957507 | 0.83 | CDK5 (0.47) | MGLLMEN1LMNAKMT2A | |
| SCHEMBL12023170 | 0.83 | CDK5 (0.47) | MGLLMEN1LMNAKMT2A | |
| SCHEMBL4752711 | 0.83 | ALDH1A1 (0.50) | NPSR1MGLLMEN1LMNAKMT2A | |
| SCHEMBL4671412 | 0.82 | MGLL (0.49) | KDM2BMGLLLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081927-A1 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS | Vitae Pharmaceuticals, Inc. (US) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008036216-A1 | PIPERIDINE DERIVATIVES AS RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2008-03-27 | — | — | WO | disclosed |