Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM2B | Q8NHM5 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3963692 | 0.83 | KDM2B (0.55) | L3MBTL1KDM2B | |
| SCHEMBL8240374 | 0.83 | KDM2B (0.55) | L3MBTL1KDM2B | |
| SCHEMBL2449231 | 0.72 | F10 (0.56) | NPC1RAB9AALDH1A1GRM5 | |
| Hydrochloric Acid SCHEMBL11023921 | 0.71 | HTR6 (0.44) | KDM2BALDH1A1 | |
| Hydrochloric Acid SCHEMBL11018151 | 0.69 | PARP1 (0.35) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL953570 | 0.69 | NPSR1 (0.59) | SLC6A2SLC6A4SLC6A3L3MBTL1KDM2B | |
| SCHEMBL31375622 | 0.68 | KDM2B (0.69) | L3MBTL1KDM2BNPC1RAB9AALDH1A1 | |
| SCHEMBL16409435 | 0.68 | KDM2B (0.69) | L3MBTL1KDM2BNPC1RAB9AALDH1A1 | |
| SCHEMBL4671412 | 0.68 | MGLL (0.49) | KDM2B | |
| Hydrochloric Acid SCHEMBL15567275 | 0.68 | NPSR1 (0.58) | SLC6A2SLC6A4SLC6A3L3MBTL1KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160436-A2 | N-[(Amino)Alkyl]-1-pyrrolidine, 1-piperidine and 1-homopiperidinecarboxamides (and thiocarboxamides) with sulphur linked substitution in the 2, 3 or 4-position | A.H. ROBINS COMPANY, INCORPORATED (US) | 1985-11-06 | — | — | EP | disclosed |