Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.74 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.74 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.74 |
| ▸ | MMP9 | P14780 | 9/20 | 0.60 |
| ▸ | MMP2 | P08253 | 8/20 | 0.60 |
| ▸ | MMP3 | P08254 | 7/20 | 0.60 |
| ▸ | MMP13 | P45452 | 7/20 | 0.60 |
| ▸ | MMP1 | P03956 | 6/20 | 0.60 |
| ▸ | MMP7 | P09237 | 6/20 | 0.60 |
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ITGAV | P06756 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4588941 | 1.00 | SLC1A3 (0.74) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL6626993 | 0.87 | KDM4E (0.57) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| Phenanthroline SCHEMBL27895995 | 0.85 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL8171825 | 0.84 | MMP2 (0.60) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL14798294 | 0.84 | SLC1A3 (0.64) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL27895996 | 0.84 | SLC1A3 (0.64) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL10765699 | 0.84 | SLC1A3 (0.64) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL14398393 | 0.81 | MMP2 (0.56) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL7293770 | 0.81 | ALDH1A1 (0.64) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL3973093 | 0.80 | MMP2 (0.82) | SLC1A3SLC1A2SLC1A1MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579487-B2 | Process for making N-sulfonated-amino acid derivatives | MERCK & CO., INC. (US) | 2009-08-25 | — | — | US | disclosed |
| EP-1747212-A4 | PROCESS FOR MAKING N-SULFONATED-AMINO ACID DERIVATIVES | MERCK & CO INC (US) | 2009-03-25 | — | — | EP | disclosed |
| US-20070219382-A1 | Process For Making N-Sulfonated-Amino Acid Derivatives | MERCK SHARP & DOHME CORP. | 2007-09-20 | — | — | US | disclosed |
| EP-1747212-A2 | PROCESS FOR MAKING N-SULFONATED-AMINO ACID DERIVATIVES | Merck and Co., Inc. (US) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005118529-A2 | PROCESS FOR MAKING N-SULFONATED-AMINO ACID DERIVATIVES | MERCK & CO., INC. (US) | 2005-12-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219382-A1 | Process For Making N-Sulfonated-Amino Acid Derivatives | ANTXR2, STS, ASNS | SLC1A3 271/4885SLC1A2 272/4885SLC1A1 517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.