Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.74 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.74 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.74 |
| ▸ | MMP9 | P14780 | 9/20 | 0.60 |
| ▸ | MMP2 | P08253 | 8/20 | 0.60 |
| ▸ | MMP3 | P08254 | 7/20 | 0.60 |
| ▸ | MMP13 | P45452 | 7/20 | 0.60 |
| ▸ | MMP1 | P03956 | 6/20 | 0.60 |
| ▸ | MMP7 | P09237 | 6/20 | 0.60 |
| ▸ | ADAMTS4 | O75173 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ITGAV | P06756 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3964633 | 1.00 | SLC1A3 (0.74) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL6626993 | 0.87 | KDM4E (0.57) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| Phenanthroline SCHEMBL27895995 | 0.85 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL8171825 | 0.84 | MMP2 (0.60) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL14798294 | 0.84 | SLC1A3 (0.64) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL27895996 | 0.84 | SLC1A3 (0.64) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL10765699 | 0.84 | SLC1A3 (0.64) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL14398393 | 0.81 | MMP2 (0.56) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL7293770 | 0.81 | ALDH1A1 (0.64) | SLC1A3SLC1A2SLC1A1MMP9MMP2 | |
| SCHEMBL3973093 | 0.80 | MMP2 (0.82) | SLC1A3SLC1A2SLC1A1MMP9MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111989331-B | Synthesis method of 2- [ (2S) -1-azabicyclo [2.2.2] oct-2-yl ] -6- (3-methyl-1H-pyrazol-4-yl) thieno [3,2-d ] pyrimidine-4 (3H) -ketone | 武田药品工业株式会社 | 2024-04-12 | — | — | CN | disclosed |
| US-20080161580-A1 | PROTECTED 3,5-DIHYDROXY-2,2-DIMETHYL-VALEROAMIDES FOR THE SYNTHESIS OF EPOTHILONES AND DERIVATIVES AND PROCESS FOR THE PRODUCTION AND THE USE | WESTERMANN JURGEN | 2008-07-03 | — | — | US | disclosed |
| US-7368568-B2 | Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for production and the use | BAYER SCHERING PHARMA AG (DE) | 2008-05-06 | — | — | US | disclosed |
| US-20050272731-A1 | Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for production and the use | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-12-08 | — | — | US | disclosed |
| US-6933385-B2 | Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use | SCHERING AG (DE) | 2005-08-23 | — | — | US | disclosed |
| US-20030158412-A1 | Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161580-A1 | PROTECTED 3,5-DIHYDROXY-2,2-DIMETHYL-VALEROAMIDES FOR THE SYNTHESIS OF EPOTHILONES AND DERIVATIVES AND PROCESS FOR THE PRODUCTION AND THE USE | DHPS, VARS1, CYP51A1 | SLC1A3 2676/4885SLC1A2 2367/4885SLC1A1 2641/4885 |
| US-20030158412-A1 | Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use | DHPS, VARS1, CYP51A1 | SLC1A3 2676/4885SLC1A2 2367/4885SLC1A1 2641/4885 |
| US-20050272731-A1 | Protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for production and the use | DHPS, VARS1, HSD17B12 | SLC1A3 1743/4885SLC1A2 1501/4885SLC1A1 1568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.