SCHEMBL3312945

SCHEMBL3312945

CC(=O)NC(=O)N1c2ccc(N(C)C)cc2Sc2cc(N(C)C)ccc21

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
SNCA P37840 1/20 0.45
BCHE P06276 12/20 0.42
ACHE P22303 1/20 0.41
MAPT P10636 2/20 0.38
GAA P10253 1/20 0.38
NOX1 Q9Y5S8 2/20 0.37
LMNA P02545 1/20 0.37
NPSR1 Q6W5P4 2/20 0.37
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL244827 0.85 MAPK1 (0.62) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL29384821 0.85 MAPK1 (0.62) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL22726424 0.84 MAPK1 (0.60) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL1208061 0.83 MAPK1 (0.67) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL29557693 0.83 MAPK1 (0.67) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL23393557 0.82 BCHE (0.61) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL29849039 0.82 BCHE (0.61) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL396464 0.80 BCHE (0.71) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL244958 0.80 KMT2A (0.59) MAPK1MEN1KMT2ATDP1L3MBTL1
SCHEMBL29386704 0.80 KMT2A (0.59) MAPK1MEN1KMT2ATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7838304-B2 Liquid reagent of color former and method of stabilizing the same ARKRAY, INC. (JP) 2010-11-23 US claimed
US-20090053823-A1 Liquid Reagent of Color Former and Method of Stabilizing The Same ARKRAY, INC. (JP) 2009-02-26 US claimed
EP-1985670-A1 LIQUID REAGENT OF COLOR FORMER AND METHOD OF STABILIZING THE SAME Arkray, Inc. (JP) 2008-10-29 EP claimed
US-20230203559-A1 METHOD FOR QUANTIFYING ETHANOLAMINE PHOSPHATE, OXIDOREDUCTASE FOR QUANTIFICATION, QUANTIFICATION COMPOSITION, QUANTIFICATION KIT, SENSOR CHIP, AND SENSOR KIKKOMAN CORPORATION (JP) 2023-06-29 US disclosed
EP-4170041-A1 METHOD FOR QUANTIFYING ETHANOLAMINE PHOSPHATE, OXIDE REDUCTASE FOR QUANTIFICATION, QUANTIFICATION COMPOSITION, QUANTIFICATION KIT, SENSOR CHIP, AND SENSOR Kikkoman Corporation (JP) 2023-04-26 EP disclosed
US-11384381-B2 Reaction accelerating agent KIKKOMAN CORPORATION (JP) 2022-07-12 US disclosed
US-11208675-B2 Reaction accelerating agent KIKKOMAN CORPORATION (JP) 2021-12-28 US disclosed
US-20190316174-A1 REACTION ACCELERATING AGENT KIKKOMAN CORPORATION (JP) 2019-10-17 US disclosed
US-20190300929-A1 REACTION ACCELERATING AGENT KIKKOMAN CORPORATION (JP) 2019-10-03 US disclosed
EP-3001190-B1 METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND METHOD FOR DETECTING A TARGET COMPONENT ARKRAY INC (JP) 2019-04-10 EP disclosed
EP-3001190-A1 METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN ARKRAY, Inc. (JP) 2016-03-30 EP disclosed
EP-2108952-B1 Method for detection of a target compound based on a redox-reaction of a phenothiazine dye ARKRAY INC (JP) 2015-10-28 EP disclosed
US-8273577-B2 Method for detecting phenothiazine-derivative color and color-developer reagent used therein ARKRAY, INC. (JP) 2012-09-25 US disclosed
US-20100112622-A1 METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN ARKRAY, INC. (JP) 2010-05-06 US disclosed
EP-2108952-A1 METHOD FOR DETECTION OF PHENOTHIAZINE DERIVATIVE DYE, AND COLOR-DEVELOPER REAGENT FOR USE IN THE METHOD Arkray, Inc. (JP) 2009-10-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100112622-A1 METHOD FOR DETECTING PHENOTHIAZINE-DERIVATIVE COLOR AND COLOR-DEVELOPER REAGENT USED THEREIN TH, TYR, HPD MAPK1 635/4885MEN1 4351/4885KMT2A 2700/4885
US-11384381-B2 Reaction accelerating agent MPO, AOX1, MAOA MAPK1 2167/4885MEN1 3767/4885KMT2A 1992/4885
US-20190316174-A1 REACTION ACCELERATING AGENT MPO, AOX1, MAOA MAPK1 2167/4885MEN1 3767/4885KMT2A 1992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.