Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965097 | 0.89 | CNR2 (0.45) | CNR2CNR1MAPTATMALDH1A1 | |
| SCHEMBL3959595 | 0.84 | CNR1 (0.47) | CNR2CNR1MAPTATMALDH1A1 | |
| SCHEMBL1464300 | 0.81 | CNR2 (0.61) | CNR2CNR1MAPTATMLMNA | |
| SCHEMBL3964990 | 0.80 | MMP2 (0.48) | CNR2CNR1MAPTCYP2C8CYP2C9 | |
| SCHEMBL1463591 | 0.78 | EEF2K (0.55) | MAPTATMALDH1A1LMNACYP2C19 | |
| SCHEMBL4017185 | 0.77 | CNR2 (0.36) | CNR2CNR1MAPTLMNA | |
| SCHEMBL1464580 | 0.76 | CNR2 (0.64) | CNR2CNR1MAPTATMALDH1A1 | |
| SCHEMBL219728 | 0.75 | EEF2K (0.55) | MAPTATMALDH1A1LMNACYP2C19 | |
| SCHEMBL3969923 | 0.75 | ALDH1A1 (0.40) | MAPTATMALDH1A1LMNACYP2C19 | |
| SCHEMBL16238871 | 0.73 | ALDH1A1 (0.51) | CNR2CNR1ALDH1A1CYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |