Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 5/20 | 0.45 |
| ▸ | CNR1 | P21554 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3959595 | 0.96 | CNR1 (0.47) | CNR2CNR1ALDH1A1MAPK1MAPT | |
| SCHEMBL3965100 | 0.89 | CNR2 (0.46) | CNR2CNR1ALDH1A1MAPK1MAPT | |
| SCHEMBL3964989 | 0.81 | MMP2 (0.47) | CNR2CNR1MAPTCYP2C8CYP2C9 | |
| SCHEMBL1464300 | 0.80 | CNR2 (0.61) | CNR2CNR1MAPTATMLMNA | |
| SCHEMBL4017182 | 0.77 | CNR2 (0.36) | CNR2CNR1MAPTSMN1; SMN2LMNA | |
| SCHEMBL1463591 | 0.77 | EEF2K (0.55) | ALDH1A1MAPTATMSMN1; SMN2LMNA | |
| SCHEMBL3962562 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPTATMSMN1; SMN2LMNA | |
| SCHEMBL1464580 | 0.75 | CNR2 (0.64) | CNR2CNR1ALDH1A1MAPTATM | |
| SCHEMBL219728 | 0.74 | EEF2K (0.55) | ALDH1A1MAPTATMLMNACYP2C19 | |
| SCHEMBL3968969 | 0.73 | ATM (0.41) | ALDH1A1MAPTATMSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |