Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702092 | 0.97 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5701442 | 0.86 | TSHR (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7639170 | 0.83 | TSHR (0.49) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5702140 | 0.83 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL35614 | 0.82 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL396293 | 0.81 | TSHR (0.38) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL4454148 | 0.81 | THRB (0.46) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL393549 | 0.81 | TSHR (0.49) | TSHRTHRBALDH1A1 | |
| SCHEMBL20555059 | 0.81 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7638067 | 0.80 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110697-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-8101789-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-01-24 | — | — | US | disclosed |
| US-20100041909-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-18 | — | — | US | disclosed |
| US-20100029972-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-04 | — | — | US | disclosed |
| EP-1510520-B1 | Preparation of branched siloxane | SHINETSU CHEMICAL CO (JP) | 2006-07-26 | — | — | EP | disclosed |
| US-6943264-B2 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL, CO., LTD. (JP) | 2005-09-13 | — | — | US | disclosed |
| US-20050049427-A1 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-03-03 | — | — | US | disclosed |
| EP-1510520-A1 | Preparation of branched siloxane | Shin-Etsu Chemical Co., Ltd. (JP) | 2005-03-02 | — | — | EP | disclosed |