SCHEMBL3965774

SCHEMBL3965774

C=C(C)OC(=O)c1ccc(O)c(O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.61
CA1 P00915 4/20 0.61
CA2 P00918 4/20 0.61
CA7 P43166 4/20 0.61
CA9 Q16790 4/20 0.61
CA14 Q9ULX7 4/20 0.61
XDH P47989 1/20 0.61
KDM4E B2RXH2 3/20 0.48
GAA P10253 2/20 0.48
MAPT P10636 2/20 0.48
PTGS2 P35354 2/20 0.48
POLB P06746 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
PTPN1 P18031 3/20 0.47
DBH P09172 1/20 0.47
RECQL P46063 1/20 0.47
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15611098 0.84 CA12 (0.69) CA12CA1CA2CA7CA9
SCHEMBL3963438 0.83 CA12 (0.42) CA12CA1CA2CA7CA9
SCHEMBL5450979 0.82 TDP1 (0.48) CA12CA1CA2CA7CA9
SCHEMBL10791915 0.79 KDM4E (0.41) CA12CA1CA2CA7CA9
SCHEMBL8814440 0.79 CA12 (0.57) CA12CA1CA2CA7CA9
SCHEMBL9008922 0.79 TDP1 (0.41) MAPTPOLBL3MBTL1ESR1ESR2
SCHEMBL9426971 0.78 CA12 (0.52) CA12CA1CA2CA7CA9
Methyl Protocatechuate SCHEMBL29360855 0.76 CA1 (1.00) CA12CA1CA2CA7CA9
SCHEMBL9142402 0.76 CA12 (0.64) CA12CA1CA2CA7CA9
Methyl Protocatechuate SCHEMBL38624 0.76 CA1 (1.00) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7589170-B1 Synthesis of cyclic peptides THE UNIVERSITY OF QUEENSLAND (AU) 2009-09-15 US disclosed
EP-1115738-A4 SYNTHESIS OF CYCLIC PEPTIDES UNIV QUEENSLAND (AU) 2004-09-01 EP disclosed
EP-1115738-A1 SYNTHESIS OF CYCLIC PEPTIDES THE UNIVERSITY OF QUEENSLAND (AU) 2001-07-18 EP disclosed
WO-2000018790-A1 SYNTHESIS OF CYCLIC PEPTIDES THE UNIVERSITY OF QUEENSLAND (AU) 2000-04-06 WO disclosed