Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2804396 | 0.74 | MAPK1 (0.60) | SMN1; SMN2MAPK1TSHRCYP2C9MAPT | |
| SCHEMBL2805733 | 0.72 | TSHR (0.58) | SMN1; SMN2MAPK1TSHRCYP2C9MAPT | |
| SCHEMBL12203799 | 0.67 | MAPK1 (0.49) | SMN1; SMN2MAPK1TSHRCYP2C9MAPT | |
| SCHEMBL25121396 | 0.67 | MAPK1 (0.60) | SMN1; SMN2MAPK1TSHRCYP2C9MAPT | |
| SCHEMBL4662128 | 0.65 | CYP2C19 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL4660712 | 0.65 | CYP2C19 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL4661900 | 0.65 | CYP2C19 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL4661890 | 0.65 | CYP2C19 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL4660714 | 0.65 | CYP2C19 (0.32) | ALDH1A1L3MBTL1 | |
| SCHEMBL13360724 | 0.65 | MAPK1 (0.43) | SMN1; SMN2MAPK1TSHRCYP2C9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2079708-A2 | ACYL AMINOIMIDAZOLES AND ACYL AMINOTHIAZOLES | Bayer HealthCare AG (DE) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008043533-A2 | ACYL AMINOIMIDAZOLES AND ACYL AMINOTHIAZOLES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-04-17 | — | — | WO | disclosed |