SCHEMBL2805733

SCHEMBL2805733

O=C1CC(C(=O)O)C2(CCCC2)O1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.58
MAPT P10636 2/20 0.58
MAPK1 P28482 2/20 0.58
CYP2C9 P11712 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.57
LMNA P02545 3/20 0.55
CASP6 P55212 1/20 0.52
HSD17B10 Q99714 1/20 0.52
POLB P06746 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
KDM4E B2RXH2 2/20 0.48
HPGD P15428 1/20 0.42
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2804396 0.98 MAPK1 (0.60) TSHRMAPTMAPK1CYP2C9SMN1; SMN2
SCHEMBL25121396 0.79 MAPK1 (0.60) TSHRMAPTMAPK1CYP2C9SMN1; SMN2
SCHEMBL26159955 0.73 MAPT (0.72) TSHRMAPTMAPK1CYP2C9SMN1; SMN2
SCHEMBL546932 0.72 LMNA (0.59) TSHRMAPTMAPK1CYP2C9SMN1; SMN2
SCHEMBL3966355 0.72 SMN1; SMN2 (0.46) TSHRMAPTMAPK1CYP2C9SMN1; SMN2
SCHEMBL12203799 0.68 MAPK1 (0.49) TSHRMAPTMAPK1CYP2C9SMN1; SMN2
SCHEMBL8889987 0.66 SMN1; SMN2 (0.43) TSHRSMN1; SMN2LMNAKDM4EALDH1A1
SCHEMBL18175953 0.64 SMN1; SMN2 (0.36) TSHRMAPTMAPK1CYP2C9SMN1; SMN2
SCHEMBL1634054 0.63 LMNA (0.39) TSHRCYP2C9LMNAKDM4EHPGD
SCHEMBL22834649 0.63 MAPT (0.31) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
CN-115903382-A Photoresist composition and pattern forming method 罗门哈斯电子材料有限责任公司 2023-04-04 CN disclosed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 TSHR 4385/4885MAPT 2575/4885MAPK1 2309/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB TSHR 4263/4885MAPT 2140/4885MAPK1 4102/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA TSHR 2885/4885MAPT 3115/4885MAPK1 2694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.