SCHEMBL2804396

SCHEMBL2804396

O=C1CC(C(=O)O)C2(CCCCC2)O1

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.60
TSHR P16473 2/20 0.60
CYP2C9 P11712 1/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
MAPT P10636 2/20 0.56
LMNA P02545 3/20 0.54
CASP6 P55212 1/20 0.51
HSD17B10 Q99714 1/20 0.51
POLB P06746 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 2/20 0.47
HPGD P15428 1/20 0.44
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2805733 0.98 TSHR (0.58) MAPK1TSHRCYP2C9SMN1; SMN2MAPT
SCHEMBL25121396 0.77 MAPK1 (0.60) MAPK1TSHRCYP2C9SMN1; SMN2MAPT
SCHEMBL3966355 0.74 SMN1; SMN2 (0.46) MAPK1TSHRCYP2C9SMN1; SMN2MAPT
SCHEMBL26159955 0.72 MAPT (0.72) MAPK1TSHRCYP2C9SMN1; SMN2MAPT
SCHEMBL12203799 0.71 MAPK1 (0.49) MAPK1TSHRCYP2C9SMN1; SMN2MAPT
SCHEMBL546932 0.71 LMNA (0.59) MAPK1TSHRCYP2C9SMN1; SMN2MAPT
SCHEMBL13360724 0.68 MAPK1 (0.43) MAPK1TSHRCYP2C9SMN1; SMN2MAPT
SCHEMBL18175953 0.67 SMN1; SMN2 (0.36) MAPK1TSHRCYP2C9SMN1; SMN2MAPT
SCHEMBL1634232 0.65 LMNA (0.38) TSHRCYP2C9LMNAKDM4EHPGD
SCHEMBL1635774 0.65 LMNA (0.38) TSHRCYP2C9LMNAKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US claimed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US claimed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US claimed
US-8968711-B2 Cosmetic or dermatological composition comprising a polymer bearing junction groups, and cosmetic treatment process L'OREAL (FR) 2015-03-03 US disclosed
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT L'OREAL (FR) 2010-10-28 US disclosed
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS L'OREAL (FR) 2010-09-23 US disclosed
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION L'OREAL (FR) 2009-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100239509-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS CUTA, SUCLG1, KRT18 MAPK1 2309/4885TSHR 4385/4885CYP2C9 2540/4885
US-20090028807-A1 COMPOSITION COMPRISING A POLYCONDENSATE, METHOD OF TREATMENT, POLYCONDENSATE, AND METHOD OF PREPARATION CUTA, SYMPK, TPRKB MAPK1 4102/4885TSHR 4263/4885CYP2C9 4541/4885
US-20100272660-A1 COSMETIC OR PHARMACEUTICAL COMPOSITION COMPRISING A POLYCONDENSATE, THE SAID POLYCONDENSATE AND METHOD OF COSMETIC TREATMENT ACMSD, CUTA, PCCA MAPK1 2694/4885TSHR 2885/4885CYP2C9 431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.