Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.33 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7035293 | 0.94 | GPR3 (0.39) | GPR3HTR2APOLBACHECHRM2 | |
| Hydrochloric Acid SCHEMBL967246 | 0.83 | GPR3 (0.31) | GPR3HTR2A | |
| Hydrochloric Acid SCHEMBL394655 | 0.83 | GPR3 (0.31) | GPR3HTR2A | |
| Hydrochloric Acid SCHEMBL29790325 | 0.83 | GPR3 (0.31) | GPR3HTR2A | |
| Hydrochloric Acid SCHEMBL396459 | 0.80 | HTR2A (0.33) | GPR3HTR2ACHRM2CHRM1SLC6A2 | |
| SCHEMBL7032620 | 0.75 | KDM4E (0.32) | HTR2ACHRM2CHRM1SLC6A2ADRA1A | |
| Hydrochloric Acid SCHEMBL7109703 | 0.75 | HTR2A (0.38) | GPR3HTR2APOLBKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL966582 | 0.73 | KDM1A (0.33) | HTR1ASLC6A2SLC6A4SLC6A3KMT2A | |
| Hydrochloric Acid SCHEMBL2053671 | 0.72 | GPR3 (0.32) | GPR3HTR2APOLBACHEKMT2A | |
| Hydrochloric Acid SCHEMBL967315 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3130635-B1 | RESIN COMPOSITION, CROSS-LINKED PRODUCT, AND METHOD FOR MANUFACTURING CROSS-LINKED PRODUCT | SUMITOMO CHEMICAL CO (JP) | 2020-02-26 | — | — | EP | disclosed |
| US-9909002-B2 | Resin composition, cross-linked product, and method for manufacturing cross-linked product | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-03-06 | — | — | US | disclosed |
| US-20170121516-A1 | RESIN COMPOSITION, CROSS-LINKED PRODUCT, AND METHOD FOR MANUFACTURING CROSS-LINKED PRODUCT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-05-04 | — | — | US | disclosed |
| EP-3130635-A1 | RESIN COMPOSITION, CROSS-LINKED PRODUCT, AND METHOD FOR MANUFACTURING CROSS-LINKED PRODUCT | Sumitomo Chemical Company Limited (JP) | 2017-02-15 | — | — | EP | disclosed |
| US-9200093-B2 | Polymerization method using surfactant-containing particle | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20140288251-A1 | POLYMERIZATION METHOD USING SURFACTANT-CONTAINING PARTICLE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-09-25 | — | — | US | disclosed |
| WO-2013085074-A1 | POLYMERIZATION METHOD USING SURFACTANT-CONTAINING PARTICLE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-06-13 | — | — | WO | disclosed |
| US-8431659-B2 | Prepolymerized catalyst for olefin polymerization, method of producing this prepolymerized catalyst and method of producing olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-04-30 | — | — | US | disclosed |
| US-20130041119-A1 | OLEFIN POLYMER PRODUCING METHOD, ETHYLENE POLYMER, AND MOLD PRODUCT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-02-14 | — | — | US | disclosed |
| US-8273677-B2 | Production process of pre-polymerized polymerization catalyst component and addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20080039602-A1 | Process for producing prepolymerization catalyst for polymerization of olefin and process for producing olefin polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-02-14 | — | — | US | disclosed |
| US-20070105711-A1 | Process for producing prepolymerization catalyst component, prepolymerization catalyst component and process for producing olefin polymer using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-10 | — | — | US | disclosed |
| US-20070100105-A1 | Melt flow rate of 0.01 to 100 g/10 min, an activation energy of flow of 50 kJ/mol or more, molecular weight distribution measured by a gel permeation chromatography of 3 or more and minute defects of 2000/m2 or less; molding materials | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1770102-A1 | Process for producing prepolymerized supported metallocene catalyst, the catalyst thereof and its use in the polymerization of olefin. | Sumitomo Chemical Company, Limited (JP) | 2007-04-04 | — | — | EP | disclosed |
| US-7122691-B2 | Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-17 | — | — | US | disclosed |
| US-20050245701-A1 | Process for producing modified particle; carrier; catalyst component for addition polymerization; process for producing catalyst for addition polymerization; and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED | 2005-11-03 | — | — | US | disclosed |
| US-20050222351-A1 | Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED | 2005-10-06 | — | — | US | disclosed |
| US-20050148459-A1 | Process for producing modified particle, carrier or catalyst component for addition polymerization, pre-polymerized catalyst component therefor, catalyst therefor, and addition polymer | SUMITOMO CHEMICAL COMPANY, LIMITED | 2005-07-07 | — | — | US | disclosed |
| US-20030069127-A1 | Modified particle,support, catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer | SUMITOMO CHEMICAL COMPANY, LIMTED (JP) | 2003-04-10 | — | — | US | disclosed |
| EP-1275662-A1 | MODIFIED PARTICLE, SUPPORT, CATALYST COMPONENT FOR ADDITION POLYMERIZATION, CATALYST FOR ADDITION POLYMERIZATION, AND PROCESS FOR PRODUCING ADDITION POLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222351-A1 | Process for producing compound, catalyst component for addition polymerization, process for producing catalyst for addition polymerization, and process for producing addition polymer | CCNT1, C5, C9 | ACHE 2420/4885CHRM2 478/4885CHRM1 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.