Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2049455 | 0.84 | MEN1 (0.30) | POLBMEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL2050881 | 0.83 | MEN1 (0.31) | GPR3HTR2APOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL15334235 | 0.76 | ADRB2 (0.30) | — | |
| Hydrochloric Acid SCHEMBL2049914 | 0.76 | GPR3 (0.34) | GPR3HTR2APOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2053777 | 0.73 | POLB (0.35) | GPR3POLBMEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL16395625 | 0.73 | — | — | |
| Hydrochloric Acid SCHEMBL15334081 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL396686 | 0.72 | GPR3 (0.40) | GPR3HTR2APOLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2046037 | 0.72 | KMT2A (0.42) | POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2053496 | 0.70 | KMT2A (0.31) | GPR3POLBMEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701595-B2 | Process for producing novel synthetic basestocks | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-07-11 | — | — | US | disclosed |
| EP-2516598-B1 | PROCESS FOR PRODUCING NOVEL SYNTHETIC BASESTOCKS | EXXONMOBIL CHEM PATENTS INC (US) | 2016-06-29 | — | — | EP | disclosed |
| US-8530712-B2 | Process for producing novel synthetic basestocks | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-09-10 | — | — | US | disclosed |
| US-20130131410-A1 | Process for Producing Novel Synthetic Basestocks | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-05-23 | — | — | US | disclosed |
| EP-2516598-A2 | PROCESS FOR PRODUCING NOVEL SYNTHETIC BASESTOCKS | Exxonmobil Chemical Patents Inc. (US) | 2012-10-31 | — | — | EP | disclosed |
| WO-2011079042-A2 | PROCESS FOR PRODUCING NOVEL SYNTHETIC BASESTOCKS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-06-30 | — | — | WO | disclosed |
| US-20110160502-A1 | Process for Producing Novel Synthetic Basestocks | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131410-A1 | Process for Producing Novel Synthetic Basestocks | PYM1, SCO2, SPIN4 | ACHE 4878/4885GPR3 2955/4885HTR2A 3452/4885 |
| US-20110160502-A1 | Process for Producing Novel Synthetic Basestocks | PYM1, SPIN4, SCO2 | ACHE 4882/4885GPR3 3124/4885HTR2A 4273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.