Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.37 |
| ▸ | EEF2K | O00418 | 2/20 | 0.35 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3962099 | 0.91 | PTGDR2 (0.40) | PTGDR2GPR27HTR6 | |
| SCHEMBL3967113 | 0.85 | PTGDR2 (0.45) | PTGDR2PTGDR | |
| SCHEMBL3973023 | 0.85 | PTGDR2 (0.66) | PTGDR2 | |
| SCHEMBL3968057 | 0.84 | PTGDR2 (0.59) | PTGDR2 | |
| SCHEMBL3967747 | 0.83 | PTGDR2 (0.46) | PTGDR2PTGDREEF2K | |
| SCHEMBL3964681 | 0.83 | PTGDR2 (0.46) | PTGDR2PTGDR | |
| SCHEMBL3971882 | 0.80 | PTGDR2 (0.46) | PTGDR2PTGDR | |
| SCHEMBL3967120 | 0.80 | PTGDR2 (0.52) | PTGDR2PTGDR | |
| SCHEMBL3968079 | 0.80 | PTGDR2 (0.49) | PTGDR2PTGDR | |
| SCHEMBL3967596 | 0.77 | PTGDR2 (0.50) | PTGDR2PTGDREEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009044147-A1 | INDOLIZINE DERIVATIVES WITH CRTH2 RECEPTOR AFFINITY FOR THE TREATMENT OF INFLAMMATORY DISEASES | ARGENTA DISCOVERY LIMITED (GB) | 2009-04-09 | — | — | WO | disclosed |
| WO-2009044147-A1 | INDOLIZINE DERIVATIVES WITH CRTH2 RECEPTOR AFFINITY FOR THE TREATMENT OF INFLAMMATORY DISEASES | ARGENTA DISCOVERY LIMITED (GB) | 2009-04-09 | — | — | WO | disclosed |