Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1465888 | 0.85 | CNR2 (0.56) | RAF1MAPK14CNR2ALDH1A1CNR1 | |
| SCHEMBL12635879 | 0.84 | KMT2A (0.58) | KMT2ANPC1RAB9AMAPK14HCRTR1 | |
| SCHEMBL1465162 | 0.81 | NLRP3 (0.52) | KMT2ANPC1RAB9AMAPK14CNR2 | |
| SCHEMBL1464930 | 0.74 | CNR2 (0.60) | MAPK14CNR2ALDH1A1CNR1 | |
| SCHEMBL4072111 | 0.73 | ALDH1A1 (0.44) | KMT2ANPC1RAB9AMAPK14CNR2 | |
| SCHEMBL3964431 | 0.73 | CNR2 (0.61) | RAF1BRAFKMT2ARAB9ACNR2 | |
| SCHEMBL775376 | 0.73 | CNR2 (0.58) | MAPK14CNR2ALDH1A1CNR1 | |
| SCHEMBL1465550 | 0.73 | CNR2 (0.67) | MAPK14CNR2ALDH1A1CNR1 | |
| SCHEMBL1464184 | 0.72 | MAPK14 (0.47) | MAPK14CNR2ALDH1A1MMP1MMP9 | |
| SCHEMBL1464909 | 0.71 | CNR2 (0.57) | KMT2ACNR2MEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | disclosed |